Research reveals how synthesized plankton molecules inhibit cancer proteins
Researchers at the Department of Chemistry, Scripps Research, California, have discovered how to harness the toxic power of plankton to manufacture anti-cancer molecules.
Researchers at the Department of Chemistry, Scripps Research, California, have discovered how to harness the toxic power of plankton to manufacture anti-cancer molecules.
In a study published in the journal Genes & Diseases, researchers from Southwest University, and Southwest Medical University investigated PRMT1, a protein previously known to be overexpressed in gastric cancer cells. Using ...
Oct 9, 2023
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Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote ...
Oct 6, 2023
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Researchers at Mays Cancer Center at The University of Texas Health Science at San Antonio (UT Health San Antonio) have identified protein markers that could signal for early development of metastatic lung cancer, providing ...
Oct 5, 2023
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Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can ...
Oct 3, 2023
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University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhancer reprogramming, occurs ...
Sep 29, 2023
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Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion oncoproteins spontaneously form ...
Sep 28, 2023
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Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer. Patients with melanoma or bladder cancer whose tumor cells lack a functioning version of the gene tend not to respond ...
Sep 28, 2023
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Researchers at Baylor College of Medicine have developed a new compound called d16 that can reduce tumor growth and overcome therapeutic resistance in mutant p53-bearing cancers in the lab. The findings, published in the ...
Sep 27, 2023
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Investigators led by Kathleen Green, Ph.D., the Joseph L. Mayberry, Sr., Professor of Pathology and Toxicology, have discovered novel intercellular "crosstalk" between epidermal keratinocytes and melanoma cells that promote ...
Sep 22, 2023
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