Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medications. This is the case, for example, with alpelisib, a drug that has been approved for ...
Apr 11, 2023
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Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer. PSMA is a protein on the cell surface ...
Apr 10, 2023
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Colorectal cancer (CRC) causes nearly 500,000 deaths every year across the globe. Although CRC is predominantly associated with old age and poor dietary habits, the precise pathophysiological mechanisms that contribute to ...
Apr 10, 2023
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Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex. Mutations in the same genes can lead to different subtypes of tumors in different people. Currently, scientists don't ...
Apr 10, 2023
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A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs. The integrated-gut-liver-on-a-chip (iGLC) ...
Apr 7, 2023
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Much of the research on new cancer treatments in the last two decades has focused on genetic targets that allow cancers to grow and spread by altering cell signaling or shutting off tumor suppressors. There is a growing body ...
Apr 7, 2023
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Two key proteins linked to cell division can reliably predict disease recurrence in prostate cancer after radiotherapy treatment, according to new research.
Apr 4, 2023
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A team of Harvard and Sloan Kettering scientists has developed compounds that can target and degrade proteins associated with acute myeloid leukemia (AML) and nearly doubled the life expectancy of mice with cancer in laboratory ...
Apr 3, 2023
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In a world first, Newcastle researchers have discovered the mechanisms acute myeloid leukemia (AML) cells use to produce "free radicals"—the byproduct of a cell process that aggressively fuels the growth of cancer cells ...
Mar 29, 2023
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Cancer-associated genes called oncogenes are well known to stimulate cell growth and division—causing tumors to balloon and spread. But now, researchers at the Stanford School of Medicine and Sarafan ChEM-H have found that ...
Mar 24, 2023
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