Researchers to develop next generation immunotherapy for children with deadly solid tumors
Recently, research using adoptive T-cell immunotherapy in blood cancers have shown success, most notably in the case of a seven-year-old girl whose leukemia went into remission using altered T-cells and a disabled HIV virus. ...
Cancer
Apr 03, 2013 |
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Insights into the immune system, from the fates of individual T cells
By charting the differing fates of individual T cells, researchers have shown that previously unpredictable aspects of the adaptive immune response can be effectively modeled. The crucial question: What determines ...
Medical research
Mar 20, 2013 |
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Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa
Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.
Cancer
Mar 15, 2013 |
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Revolutionary techniques could help harness patients' own immune cells to fight disease
The human body contains immune cells programmed to fight cancer and viral infections, but they often have short lifespans and are not numerous enough to overcome attacks by particularly aggressive malignancies ...
Medical research
Jan 03, 2013 |
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Researchers say effective immunotherapy for melanoma hinges on blocking suppressive factors
(Medical Xpress)—Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of myeloid-derived suppressor cells ...
Immunology
Dec 11, 2012 |
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Moffitt researchers identify unique immune gene signature across thousands of patients' solid tumors
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered a unique immune gene signature that can predict the presence of microscopic lymph node-like structures in metastatic melanoma. The presence of these ...
Genetics
Oct 25, 2012 |
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Mouse model exposes a new type of T cell to target melanoma
Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow ...
Cancer
Oct 24, 2012 |
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Researchers study 'ACT TIL' approach to treating metastatic melanoma
Researchers at Moffitt Cancer Center have carried out a clinical trial in which patients with metastatic melanoma were given chemotherapy and an immunotherapy of adoptive cell transfer (ACT) with tumor infiltrating lymphocytes ...
Immunology
Oct 17, 2012 |
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New study to combat the most common form of liver cancer
Scientists at the University of Southampton are to investigate the best way to use natural killer cells (NK) to target the most common form of liver cancer.
Cancer
Oct 12, 2012 |
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Combination therapy delivers one-two punch to skin cancer, boosting anti-tumor activity
(Medical Xpress) -- Treating metastatic melanoma by combining immunotherapy with a drug that inhibits the cancer-spreading activity of a common gene mutation significantly increased survival times in an animal model, according ...
Cancer
Aug 16, 2012 |
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Novel technique for delivering multiple cancer treatments may solve hurdle for combinatorial drug therapies
Cancers are notorious for secreting chemicals that confuse the immune system and thwarting biological defenses.
Cancer
Jul 15, 2012 |
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Researchers find success with new immune approach to fighting some cancers
A national research collaboration of senior researchers, including a researcher from Moffitt Cancer Center, has found that 20 to 25 percent of "heavily pre-treated" patients with a variety of cancers who enrolled in a clinical ...
Cancer
Jun 13, 2012 |
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FDA-approved drug daclizumab makes established cancer vaccine work better
A team from the Perelman School of Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania found that the FDA-approved drug daclizumab improved the survival of breast cancer patients taking ...
Cancer
May 16, 2012 |
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Cancer vaccine combination therapy shows survival benefit in breast cancer
A vaccine that targets cancer cells in combination with the drug letrozole, a standard hormonal therapy against breast cancer, significantly increased survival when tested in mice, a team of UC Davis investigators has found.
Cancer
May 15, 2012 |
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'Thin red line' around breast cancer
A pioneering approach to imaging breast cancer in mice has revealed new clues about why the human immune system often fails to attack tumors and keep cancer in check. This observation, by scientists at the ...
Cancer
May 02, 2012 |
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