TG4050, a personalized neoantigen vaccine, induced tumor-specific immune responses and led to low rates of disease relapse in patients with surgically resected HPV-negative head and neck squamous cell cancer (HNSCC), according ...
Apr 9, 2024
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14
A vaccine has shown potential to prevent relapse of KRAS-mutated pancreatic and colorectal cancers for patients who had previously undergone surgery, according to a Phase I trial led by researchers at The University of Texas ...
Jan 9, 2024
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117
Late-breaking research reveals a major treatment advance for adults with newly diagnosed B lineage acute lymphoblastic leukemia (ALL). The randomized phase 3 study E1910 evaluated blinatumomab immunotherapy in patients with ...
Dec 13, 2022
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3
Colon cancer is the third most common cancer in the world, with about 2 million new cases each year. Most patients are diagnosed when the tumor is still located in the colon or rectum. These tumors are removed by surgery, ...
Nov 9, 2022
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A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led ...
Nov 3, 2022
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35
Medulloblastoma is the most common form of malignant brain tumor in children, which often can be cured with operation, radiation and chemotherapy. But a distinct type of medulloblastoma has an increased risk of becoming resistant ...
Oct 28, 2022
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10
A team of scientists and doctors from the KK Women's and Children's Hospital (KKH), Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and the Institute for Health Innovation and Technology has ...
Oct 5, 2022
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39
Researchers at Baylor College of Medicine and collaborating institutions have engineered immune cells to control two major life-threatening complications, namely graft-vs-host disease (GvHD) and cancer relapse, which typically ...
Sep 27, 2022
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15
In a new study from Vanderbilt University Medical Center, 10-second videos of white blood cell motion in the skin's microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would ...
Mar 29, 2022
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106
Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that ...
Dec 17, 2020
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