Oncology & Cancer

Assessing breast cancer risk

The genetic risk of breast cancer has been in the news lately. Researchers at the Mayo Clinic Comprehensive Cancer Center are working toward pinpointing individuals' risk of developing breast cancer.

Oncology & Cancer

Exploring the deep link between cancer and genetics

As the cost of genome and exome sequencing falls, its use in characterizing rare diseases and personalizing cancer treatment, for example, is becoming far more frequent. But such analyses may throw up findings unrelated to ...

Genetics

Gene that shapes mutation rate found in mice

Every organism is born with a few mutations in their genome that differ genetically from both of their parents. Such changes in an individual's genetic code create the diversity that allows nature to select advantageous traits ...

Oncology & Cancer

New candidate cancer genes identified using math models

Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of ...

Oncology & Cancer

New breast cancer targets

Genome-wide association studies (GWAS) have identified more than 150 genetic variations associated with increased risk for breast cancer. Most of these variants are not located in protein-coding gene regions but are assumed ...

Oncology & Cancer

Accurately diagnosing genetic disease prevents cancer, saves lives

A single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than the traditional multiple, sequential testing approach, according to new clinical data reported by The ...

Oncology & Cancer

New report: Labs differ widely in BRCA testing protocols

An international survey of genetic testing labs shows that - despite the availability of BRCA1 and BRCA2 testing for more than two decades - global protocols and standards are surprisingly inconsistent when it comes to analyzing ...

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