New targeted therapy for advanced prostate cancer shows anti-tumor activity in clinical trials
Few available treatment options exist once prostate cancer has spread to other parts of the body and has failed to respond to therapies that involve blocking the male hormone androgen. Patients with advanced, hormone-refractory ...
Cancer
Nov 07, 2012 |
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New monoclonal antibody inhibits tumor growth in advanced solid tumors in phase I clinical trial
A newly developed antibody targeting a signalling pathway that is frequently active in solid tumours has shown encouraging signs of efficacy in its first trial in humans, researchers will report at the 24th EORTC-NCI-AACR ...
Cancer
Nov 06, 2012 |
5 / 5 (2) |
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Scientists test 5,000 combinations of 100 existing cancer drugs to find more effective treatments
Scientists in the United States have tested all possible pairings of the 100 cancer drugs approved for use in patients in order to discover whether there are any combinations not tried previously that are effective in certain ...
Cancer
Nov 06, 2012 |
4.3 / 5 (3) |
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Hedgehog pathway key in tamoxifen-resistant breast CA
(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh ...
Cancer
Nov 06, 2012 |
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Stereotactic radiosurgery shows promise for kidney cancer
A first-of-its-kind clinical trial conducted at University Hospitals (UH) Case Medical Center Seidman Cancer Center has shown encouraging results for the use of stereotactic radiosurgery to treat kidney cancer. This non-invasive ...
Cancer
Oct 31, 2012 |
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Recent findings may help to fight melanoma's resistance to chemotherapy
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...
Cancer
Oct 31, 2012 |
1 / 5 (1) |
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New developments reveal a molecule with a promising function in terms of cancer treatment.
Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...
Cancer
Oct 30, 2012 |
5 / 5 (1) |
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Researchers develop new drug delivery system for bladder cancer using nanoparticles
A team of UC Davis scientists has shown in experimental mouse models that a new drug delivery system allows for administration of three times the maximum tolerated dose of a standard drug therapy for advanced bladder cancer, ...
Cancer
Oct 25, 2012 |
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Scientists block stomach tumor growth
(Medical Xpress)—Monash Institute of Medical Research scientists may have discovered a way of blocking stomach tumours from growing and spreading, according to a paper published in the highly-prestigious ...
Cancer
Oct 16, 2012 |
1 / 5 (1) |
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Proteins in DNA damage response network targeted for new therapies, researchers say
(Medical Xpress)—Researchers at Moffitt Cancer Center and colleagues at the University of South Florida; Duke University; Johns Hopkins University; the Brazilian National Cancer Institute; and the Rio de Janeiro Federal ...
Medical research
Oct 16, 2012 |
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Anti-cancer drug fights immune reaction in some infants with Pompe disease
Adding a third anti-cancer agent to a current drug cocktail appears to have contributed to dramatic improvement in three infants with the most severe form of Pompe disease—a rare, often-fatal genetic disorder ...
Genetics
Oct 11, 2012 |
3.5 / 5 (2) |
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First WGS of multiple pancreatic cancer patients outlined in new study
Whole genome sequencing—spelling out all 3 billion letters in the human genome—"is an obvious and powerful method for advancing our understanding of pancreatic cancer," according to a new study from TGen, Mayo Clinic ...
Cancer
Oct 10, 2012 |
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Endotrophin links obesity to breast cancer progression
Fat cells (adipocytes) surround breast tumors and contribute to tumor growth by expressing factors that aid oncogenesis. Col6 is a protein that is highly expressed in adipocytes and its expression is further increased in ...
Cancer
Oct 08, 2012 |
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Breakthrough in understanding lung cancer vulnerabilities points the way to new targeted therapy
More effective treatments for one of the deadliest forms of cancer are one step closer thanks to groundbreaking research from an international collaborative study.
Cancer
Oct 01, 2012 |
5 / 5 (5) |
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Aggressive cancer exploits MYC oncogene to amplify global gene activity
Whitehead Institute researchers have determined the mechanism used by c-Myc to increase the expression of all active genes in cancer cells. Elevated levels of c-Myc are linked to increased rates of metastasis, disease recurrence, ...
Cancer
Sep 27, 2012 |
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