Cancer cells are characterized by their aggressiveness: they grow rapidly and spread to other parts of the body. To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates ...
Mar 7, 2024
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A pioneering Phase I CAR T cell therapy trial for the treatment of glioblastoma at City of Hope demonstrates promising clinical activity against incurable brain tumors, according to research published in Nature Medicine.
Mar 7, 2024
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Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer ...
Mar 7, 2024
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Chimeric antigen receptor (CAR)-T cell therapy is a potent emerging weapon against cancer, altering patients' T cells so they can better find and destroy tumor cells. But CAR-T cell therapy doesn't work well in every cancer—including ...
Mar 1, 2024
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A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation. The results, ...
Feb 23, 2024
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Bladder cancer is one of the more common cancers worldwide. It is considered a major health care problem with a high financial burden. Of these cases, 75% are non-muscle-invasive, which characterizes dangerous diseases with ...
Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...
Feb 21, 2024
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In the ever-evolving battle against cancer, immunotherapy presents a turning point. It began with harnessing the body's immune system to fight cancer, a concept rooted more than a century ago but only gaining significant ...
Feb 21, 2024
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Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients ...
Feb 16, 2024
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A novel three-drug combination achieved notable responses in patients with advanced HER2-negative breast cancer, according to new research directed by investigators from the Johns Hopkins Kimmel Cancer Center.
Feb 14, 2024
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