Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
Platinum compounds, such as cisplatin and carboplatin, induce DNA cross-linking, prohibiting DNA synthesis and repair in rapidly dividing cells. They are first line therapeutics in the treatment of many solid tumors, but ...
Cancer
Apr 15, 2013 |
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Peptides for the treatment of severe diseases
A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively ...
Medical research
Apr 15, 2013 |
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Whole genome sequencing finds new mutations to blame for a majority of brain tumor subtype
Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors ...
Genetics
Apr 14, 2013 |
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Icy therapy spot treats cancer in the lung
Frozen balls of ice can safely kill cancerous tumors that have spread to the lungs, according to the first prospective multicenter trial of cryoablation. The results are being presented at the Society of Interventional Radiology's ...
Cancer
Apr 14, 2013 |
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Immune response linked to key enzyme
(Medical Xpress)—A previously unknown function of a family of enzymes familiar to biologists may contribute to scientists' understanding of signaling molecules involved in the body's immune response and ...
Immunology
Apr 12, 2013 |
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Research shows promise for microwave ablation (MWA) to relieve painful bone and soft-tissue tumors
First-of-its-kind research presented today showed microwave ablation (MWA) therapy cut pain in half for patients with painful bone and soft-tissue tumors and took less time to complete than radiofrequency ablation. Pain relief ...
Cancer
Apr 11, 2013 |
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Genetic master controls expose cancers' Achilles' heel
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...
Cancer
Apr 11, 2013 |
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Study finds new drug target for metastatic breast cancer
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...
Cancer
Apr 11, 2013 |
5 / 5 (1) |
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Gauging brain cancer survival time may get easier, study says
(HealthDay)—Life expectancy of people with aggressive brain cancer may be easier to determine with a new method under development at the University of Alabama at Birmingham, researchers say.
Cancer
Apr 10, 2013 |
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Pfizer breast cancer drug gets breakthrough label
Pfizer Inc. says its experimental pill for advanced, often deadly breast cancer has been designated as a breakthrough therapy by the Food and Drug Administration.
Cancer
Apr 10, 2013 |
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Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...
Cancer
Apr 10, 2013 |
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Insights into an abnormally edited RNA molecule may yield new weapons against a hard-to-kill cancer
Diagnosis of the brain cancer glioblastoma multiforme (GBM) is particularly bad news for patients due to limited available medical options and poor outcomes. Even treatments that can eliminate other malignancies, ...
Cancer
Apr 10, 2013 |
4.5 / 5 (2) |
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Researchers find some lung cancers linked to common virus
A common virus known to cause cervical and head and neck cancers may also trigger some cases of lung cancer, according to new research presented by Fox Chase Cancer Center at the AACR Annual Meeting 2013 on Wednesday, April ...
Cancer
Apr 10, 2013 |
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Association between genetic mutation and risk of death for patients with thyroid cancer
Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association ...
Cancer
Apr 09, 2013 |
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Clinical trial finds new class of cancer drugs safe and effective
The safety and preliminary efficacy of a new class of tumor fighting drugs were reported today by Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials and the Translational Genomics Research Institute (TGen).
Cancer
Apr 09, 2013 |
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