Periodic bursts of genetic mutations drive prostate cancer
Cancer is typically thought to develop after genes gradually mutate over time, finally overwhelming the ability of a cell to control growth. But a new closer look at genomes in prostate cancer by an international team of ...
Cancer
Apr 25, 2013 |
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Researchers discover link between inherited endocrine tumor syndrome and well-studied cell pathway
(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of ...
Cancer
Apr 24, 2013 |
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A different view of cancer cells: New study measures physical changes in tumor cells as they become metastatic
Most cancer deaths are caused by metastatic tumors, which break free from the original cancer site and spread throughout the body. For that to happen, cancer cells must undergo many genetic and physical changes.
Cancer
Apr 23, 2013 |
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Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
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Radioactive bacteria targets metastatic pancreatic cancer
Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them. The ex ...
Cancer
Apr 22, 2013 |
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Metastasis stem cells in the blood of breast cancer patients discovered
Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...
Cancer
Apr 22, 2013 |
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Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma
A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.
Cancer
Apr 19, 2013 |
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Molecule treats leukemia by preventing cancer cell repair, scientists report
(Medical Xpress)—Researchers at The Jackson Laboratory have identified a molecule that prevents repair of some cancer cells, providing a potential new "genetic chemotherapy" approach to cancer treatment ...
Cancer
Apr 17, 2013 |
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Transcription factors regulating blood oxygen linked to melanoma metastases
Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.
Cancer
Apr 16, 2013 |
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New kidney cancer subtypes discovered
Researchers with the Institute of Urologic Oncology and the Department of Urology at UCLA have classified kidney cancer into several unique subtypes, a finding that will help physicians tailor treatment to ...
Cancer
Apr 16, 2013 |
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Gene-expression signature may signify risk for recurrence, metastasis in prostate cancer
A team led by Massachusetts General Hospital (MGH) researchers has identified a genetic signature that appears to reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer. If confirmed ...
Cancer
Apr 15, 2013 |
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Cancer cell metabolism kills
Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...
Cancer
Apr 15, 2013 |
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Immune response linked to key enzyme
(Medical Xpress)—A previously unknown function of a family of enzymes familiar to biologists may contribute to scientists' understanding of signaling molecules involved in the body's immune response and ...
Immunology
Apr 12, 2013 |
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Genetic master controls expose cancers' Achilles' heel
In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...
Cancer
Apr 11, 2013 |
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Two-drug combo more effective in treating sarcomas, study shows
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report ...
Cancer
Apr 09, 2013 |
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