Even for killer T cells—specialized immune cells—seeking and destroying cancer cells around the clock can be exhausting. If scientists can understand why killer T cells become exhausted, then they can create more resilient ...
Sep 20, 2023
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The resistance to cancer treatment is often credited to the heterogenous cellular nature within a tumor. The tumor cell-cell interaction and cell-microenvironment have a key role in the invasion and progression of tumors ...
Glioblastoma is a swift and aggressive brain cancer, with an average life expectancy of about one year after diagnosis. It's difficult to treat, in part because the cellular makeup of each tumor varies greatly from person ...
Aug 23, 2023
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A study by researchers from Karolinska Institutet and physicians from Karolinska Hospital shows that a capsule of connective tissue around liver metastases from colorectal cancer improves patient survival and represents a ...
Aug 22, 2023
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A study from the University of Michigan Rogel Cancer Center uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer.
Aug 14, 2023
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The National Institutes of Health is releasing a comprehensive dataset that standardizes genomic, proteomic, imaging, and clinical data from individual studies of more than 1,000 tumors across 10 cancer types. Researchers ...
Aug 14, 2023
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Penile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typically begin with platinum chemotherapy. Immune checkpoint inhibitors (ICIs) are novel therapies ...
Aug 11, 2023
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Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that creates random mutations throughout the genome that drive resistance to targeted treatments, a team led by UT Southwestern Medical ...
Aug 7, 2023
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A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, ...
Aug 3, 2023
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New research, published in Nature Genetics, shows that more people may benefit from PARP inhibitor drugs, like olaparib, which are already used to treat some breast, ovarian and prostate cancer patients who have inherited ...
Aug 1, 2023
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