Chimeric antigen receptor (CAR) T cells have transformed the treatment of refractory blood cancers. These genetically engineered immune cells seek out and destroy cancer cells with precision. Now, scientists at Memorial Sloan ...
Jun 17, 2020
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Pancreatic ductal adenocarcinoma (PDAC) cells maintain a high level of autophagy or degradation, allowing them to thrive in severely limiting microenvironments. However, the process via which autophagy promotes pancreatic ...
Dana-Farber Cancer Institute scientists have successfully disrupted the function of a cancer gene involved in the formation of most human tumors by tampering with the gene's "on" switch and growth signals, rather than targeting ...
Sep 9, 2011
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The human hand is remarkable. Not only does it allow us to throw, grab, climb and pick things up, it can also be a measure of health. Using hand-grip strength—which assesses the amount of force a person can generate with ...
Oct 15, 2020
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Cancer, in all its forms, seems to always involve uncontrolled cell growth; but there are thousands of ways in which cells can lose control of their proliferation in the first place. Among a huge variety of proteins known ...
Mar 22, 2019
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New research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australia almost quadrupled between 1983 and 2017, foreshadowing a growing ...
Sep 9, 2022
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An international group of researchers investigated why mutations often associated with renal cancer result specifically in renal cancer, instead of other cancer types.
Aug 9, 2022
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A Penn- and MIT-led team explained how rapamycin, a drug that extends mouse lifespan, also causes insulin resistance. The researchers showed in an animal model that they could, in principle, separate the effects, which depend ...
Mar 29, 2012
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Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system ...
Nov 23, 2022
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Researchers on Mayo Clinic's Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.
Mar 14, 2016
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