The heart is an amazingly adaptable organ, responding to the needs of the organism throughout life, such as through periods of increased demand by pumping harder, faster, and also growing to accommodate longer-term requirements ...
Nov 28, 2016
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Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study published today in Science Translational Medicine.
Jun 27, 2012
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Science has long known that recovery from experimental heart attacks is improved by injection of a mixture of heart muscle cells, endothelial cells and smooth muscle cells, yet results have been limited by poor engraftment ...
Sep 29, 2020
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Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar. While this scar works well initially to avoid ...
Jan 30, 2020
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A faster, more cost-efficient, and more accurate method of examining the effectiveness of human pluripotent stem-cell-derived cardiac muscle cells has been discovered, according to researchers from Penn State.
Dec 19, 2018
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The human heart is particularly vulnerable to viruses. That's because cardiac myocytes, the heart muscle cells that give your heart its ability to "beat," have one major weakness – they don't reproduce themselves to repair ...
Sep 29, 2017
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The key objective of the EU-funded CARE-MI project, which was completed in September 2015, was to evaluate the safety and efficacy of AlloCSC-01, a suspension of allogeneic human cardiac stem cells (CSCs) in patients who ...
Nov 25, 2015
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In a recent issue of Science Translational Medicine, Brian Polizzotti, PhD, Bernhard Kuhn, MD, Sangita Choudhury, PhD, and colleagues affiliated with the Boston Children's Hospital's Translational Research Center report that ...
Apr 28, 2015
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An unexpected finding that links a structural heart protein to gene regulation following heart stress suggests potential new avenues for developing heart failure therapies.
Nov 8, 2018
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Scientists at Johns Hopkins have shown in laboratory experiments in mice that blocking the action of a signaling protein deep inside the heart's muscle cells blunts the most serious ill effects of high blood pressure on the ...
May 2, 2011
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