Cardiology

Lack of CHD4 leads to abnormal myofibrils, heart defects

(HealthDay)—The absence of CHD4 in heart cells results in inappropriate production of non-cardiac muscle proteins, which subsequently leads to heart defects, according to an animal study published recently in the Proceedings ...

Cardiology

Heart attack: Substitute muscle thanks to stem cells

Myocardial infarction – commonly known as a heart attack – is still one of the main causes of death. According to the Federal Statistical Office, more than 49,00 people died of its consequences. And yet the mortality ...

Cardiology

Patient-friendly and accurate cardiac damage diagnosis

Systemic inflammatory diseases, such as lupus, often cause cardiac damage that goes undetected. An international research team headed by the Institute for Experimental and Translational Cardiovascular Imaging at the University ...

Cardiology

The molecules that energize babies' hearts

A metabolic process that provides heart muscle with energy fails to mature in newborns with thickened heart walls, according to a Japan–Canada research team.

Cardiology

Getting to the heart of congenital cardiac defects

Heart defects are the most common type of birth defect, and can be caused by mutations in the gene CHD4. Researchers at the UNC School of Medicine have now revealed key molecular details of how CHD4 mutations lead to heart ...

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