Assistant Professor Shunsuke Funakoshi, Associate Professor Yoshinori Yoshida, and their research team have identified Am80 as a molecule that activates the cell cycle in cardiomyocytes to enhance cardiac tissue graft production ...
Jul 14, 2023
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Researchers at Indiana University School of Medicine are learning more about ways to prevent serious side effects from chemotherapy used to treat breast cancer patients. The work done by the Schneider lab at the Vera Bradley ...
Dec 20, 2022
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Cardiac arrhythmias are a major risk factor for sudden cardiac death, which accounts for 15% to 20% of all deaths worldwide. Causes for arrhythmias are diverse and include genetic factors, patients' physical and mental condition, ...
Jul 14, 2022
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While lower vertebrates can repair their adult hearts after a heart attack, mammals—including humans—cannot. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few days after birth because ...
Jun 24, 2022
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Twenty years ago, clinicians first attempted to regenerate a failing human heart by injecting muscle myoblasts into the heart during a bypass operation. Despite high initial hopes and multiple experimental and clinical studies ...
Nov 29, 2021
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Males and females differ in prevalence, treatment responses, and survival rates for a variety of diseases. For cardiac disease, women almost uniformly fare far worse than men. There are likely many reasons for this, and scientists ...
Oct 19, 2021
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Fatty acids are formed when fat breaks down during digestion. While many of the body's organs use glucose as their primary energy source, the heart derives most of its required energy (over 70%) from the oxidation of fatty ...
Jun 29, 2021
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The protein titin is a large structural component of the sarcomere—the machinery that mediates contraction of cardiac muscle cells. Despite its importance to the beating heart, little is known about titin turnover.
Dec 18, 2019
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Researchers from the National Institute for Physiological Sciences revealed the molecular mechanism underlying increased risk of heart failure during hemodynamic load by methylmercury exposure. They found that exposure of ...
Jun 26, 2019
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Injured hearts do not heal themselves. Heart muscle cells, or cardiomyocytes, do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Consequently, most people who had a severe heart attack ...
Feb 14, 2019
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