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News tagged with cardiovascular genetics

Researchers study under-recognised and under-treated prothrombotic condition: High platelet reactivity despite treatment

Within the past decade, the variability in pharmacodynamic response and moderate antiplatelet efficacy of clopidogrel has raised major concerns, in particular because it is associated with an increased risk for ischemic events ...

Cardiology May 06, 2013 | not rated yet | 0

Study uncovers molecular role of gene linked to blood vessel formation

University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.

Medical research Apr 29, 2013 | 5 / 5 (1) | 0 |

Niacin added to statin therapy increases HDL cholesterol levels but does not improve HDL functionality, research shows

While two large clinical trials recently showed that adding niacin to statin therapy failed to improve clinical outcomes despite a significant increase in HDL-C levels, little is known about exactly why the increased HDL-C ...

Cardiology Mar 12, 2013 | 5 / 5 (1) | 0

Zeroing in on heart disease: Innovative strategy pinpoints genes underlying cardiovascular disease risk

Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease. Researchers ...

Genetics Feb 28, 2013 | not rated yet | 0

Discovery offers unprecedented look at regulation of gene expression

(Medical Xpress)—A groundbreaking technique developed at the University of Virginia School of Medicine is allowing scientists to examine histone modifications of genetic loci – a process that regulates gene expression ...

Medical research Jan 25, 2013 | 5 / 5 (2) | 0 |

Genetic susceptibility to anthracycline-related congestive heart failure (CHF) in survivors of hematopoietic cell transp

Researchers have identified specific genetic factors that are associated with heart failure in patients who have undergone hematopoietic stem cell transplantation (HCT) for blood cancer.

Medical research Dec 09, 2012 | not rated yet | 0

Largest coronary artery disease study shows evidence of link between inflammation and heart disease

The University of Ottawa Heart Institute (UOHI) participated in the largest genetic study of Coronary Artery Disease (CAD) to date. Researchers from the CARDIoGRAMplusC4D Consortium report the identification of 15 genetic ...

Genetics Dec 03, 2012 | 3.5 / 5 (2) | 0 |

A new way of looking at Prader-Willi Syndrome

An Australian study reveals that people with the rare genetic disorder known as Prader-Willi Syndrome may have an impaired autonomic nervous system. This discovery opens up a new way of looking at the insatiable appetite ...

Diseases, Conditions, Syndromes Nov 15, 2012 | 5 / 5 (2) | 0

Obese moms give birth to heart healthier kids following bariatric surgery

Kids born to moms who have lost a substantial amount of weight after undergoing bariatric surgery have fewer cardiovascular risk factors than their siblings who were born before the weight loss surgery.

Surgery Oct 29, 2012 | not rated yet | 0

Genetic predisposition to diabetes ups risk of CVD

(HealthDay)—For patients with type 2 diabetes (T2D), having a genetic predisposition towards the disease is associated with an increased risk of cardiovascular disease (CVD), according to a study published ...

Cardiology Oct 23, 2012 | not rated yet | 0

Aspirin may slow the decline in mental capacity among elderly patients

A daily dose of acetylsalicylic acid equivalent to a fourth of an aspirin may slow the decline in intellectual capacity among elderly individuals with high cardiovascular risk. This is shown in a study by Sahlgrenska Academy, ...

Medications Oct 22, 2012 | not rated yet | 0

Aspirin may temper brain power decline in elderly women at risk of heart disease

Daily low dose aspirin could slow the decline in brain power among elderly women at high risk of heart disease, indicates observational research published in the online journal BMJ Open.

Medications Oct 03, 2012 | not rated yet | 0

Study discovers first real indicator of longevity in mammals

A team of researchers from the Spanish National Cancer Research Centre (CNIO), headed by CNIO Director María Blasco, has demonstrated in a pioneering study on mammals that longevity is defined at a molecular level by the ...

Medical research Sep 27, 2012 | 5 / 5 (1) | 1

Scientists map the genomic blueprint of the heart

Scientists at the Gladstone Institutes have revealed the precise order and timing of hundreds of genetic "switches" required to construct a fully functional heart from embryonic heart cells—providing new ...

Medical research Sep 13, 2012 | 5 / 5 (3) | 0 |

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