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New theory on genesis of osteoarthritis comes with successful therapy in mice

Scientists at Johns Hopkins have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, ...

Arthritis & Rheumatism created 21 hours ago | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Gene associated with adolescent idiopathic scoliosis identified

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian ...

Genetics created May 12, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Gene identified, responsible for a spectrum of disorders affecting the bones and connective tissue

Researchers from the RIKEN Center for Integrative Medical Sciences have identified a gene that when mutated is responsible for a spectrum of disorders affecting the bones and connective tissue. This finding ...

Genetics created May 09, 2013 | popularity not rated yet | comments 0

Researchers getting closer to growing a human heart

(Medical Xpress)—Researchers in Spain, led by doctor Francisco Fernandez-Aviles, are blazing a trail in bioengineering that could result, the Wall Street Journal reports, in human hearts, or parts of them, being grown in a lab and transplanted into live patients, within ...

Medical research created Mar 25, 2013 | popularity 5 / 5 (12) | comments 0 | with audio podcast weblog

Can stem cells help those with arthritis?

Stems cells taken from just a few grams of body fat are a promising weapon against the crippling effects of osteoarthritis.

Arthritis & Rheumatism created Apr 28, 2013 | popularity not rated yet | comments 0

Researchers use hydrogel to repair cartilage

(Medical Xpress)—Researchers in the US have created a type of hydrogel that has proven to be effective in treating patients with damaged cartilage. The gel, the team writes, in their paper published in ...

Medical research created Jan 11, 2013 | popularity 4.4 / 5 (8) | comments 1 | with audio podcast report

Nanokicking stem cells to open for new generation of orthopaedics

(Medical Xpress)—New research has shown that it is possible to grow new bone by "nanokicking" stem cells 1,000 times per second using high frequency vibrations.

Medical research created Apr 05, 2013 | popularity 5 / 5 (3) | comments 2 | with audio podcast

Team discovers new strategy to effectively treat, prevent osteoarthritis

Think new discoveries are the bee's knees? This one is even better—this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, ...

Arthritis & Rheumatism created Mar 25, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Using 3-D printing and injectable molds, bioengineered ears look and act like the real thing

Cornell bioengineers and physicians have created an artificial ear – using 3-D printing and injectable molds – that looks and acts like a natural ear, giving new hope to thousands of children born with a congenital deformity ...

Medical research created Feb 20, 2013 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Sizing up bone growth: A surprising cellular mechanism drives skeletal proportions

(Medical Xpress)—Stroll through the Harvard Museum of Natural History and gaze up at the whale skeleton looming overhead. Look down at the furry foxes curled up inside their glass display cases. Don't forget ...

Medical research created Mar 14, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

A better way to grow bone: Fresh, purified fat stem cells grow bone faster and better

UCLA stem cell scientists purified a subset of stem cells found in fat tissue and made from them bone that was formed faster and was of higher quality than bone grown using traditional methods, a finding that may one day ...

Medical research created Jun 11, 2012 | popularity 1 / 5 (1) | comments 0 | with audio podcast

Research team finds compound that can spur cartilage growth

(Medical Xpress) -- A research team from drug maker Novartis has discovered a compound that spurs cartilage growth in mice. As they describe in their paper published in the journal Science, the team has found that when a ...

Medical research created Apr 06, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast report

Nanoscale scaffolds and stem cells show promise in cartilage repair

Johns Hopkins tissue engineers have used tiny, artificial fiber scaffolds thousands of times smaller than a human hair to help coax stem cells into developing into cartilage, the shock-absorbing lining of elbows and knees ...

Medical research created Jul 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Neurosurgeons use adult stem cells to grow neck vertebrae

Neurosurgery researchers at UC Davis Health System have used a new, leading-edge stem cell therapy to promote the growth of bone tissue following the removal of cervical discs -- the cushions between the bones in the neck ...

Neuroscience created Sep 06, 2011 | popularity 5 / 5 (8) | comments 5 | with audio podcast

Researchers engineer cartilage from pluripotent stem cells

A team of Duke Medicine researchers has engineered cartilage from induced pluripotent stem cells that were successfully grown and sorted for use in tissue repair and studies into cartilage injury and osteoarthritis.

Medical research created Oct 29, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Cartilage

Cartilage is a type of dense connective tissue existing within many joints. It is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers. Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of these three main components.

Cartilage is found in many areas in the body, including the articular surface of the bones, the rib cage, the ear, the nose, the bronchial tubes and the intervertebral discs. Its mechanical properties are intermediate between bone and dense connective tissue like tendon.

Unlike other connective tissues, cartilage does not contain blood vessels. The chondrocytes are fed by diffusion, helped by the pumping action generated by compression of the articular cartilage or flexion of the elastic cartilage. Thus, compared to other connective tissues, cartilage grows and repairs more slowly.

For more information about Cartilage, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: stem cells , cells , arthritis , osteoarthritis