Arthritis & Rheumatism

Potential new drug target for the treatment of rheumatoid arthritis

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses ...

Medical research

How cartilage cells sense forceful injury

We live with the same cartilage—the tissue that connects our joints—for a lifetime. And since we can't readily make new cartilage cells, we had better figure out how to keep what we have healthy.

Medical research

Making lab-grown tissues stronger

Lab-grown tissues could one day provide new treatments for injuries and damage to the joints, including articular cartilage, tendons and ligaments.

Medical research

A new way to extract bone-making cells from fat tissue

Within our fat lives a variety of cells with the potential to become bone, cartilage, or more fat if properly prompted. This makes adipose tissue, in theory, a readily available reservoir for regenerative therapies such as ...

Medical research

Columbia engineers grow functional human cartilage in lab

Researchers at Columbia Engineering announced today that they have successfully grown fully functional human cartilage in vitro from human stem cells derived from bone marrow tissue. Their study, which demonstrates new ways ...

Medical research

Regenerating orthopedic tissues within the human body

A team of Duke University biomedical engineers has developed a polymer scaffold for growing cartilage that includes gene therapy vectors to induce stem cells to produce the growth factors they need. The new technique—biomaterial-mediated ...

Medical research

Chemical signaling simulates exercise in cartilage cells

Cartilage is notoriously difficult to repair or grow, but researchers at Duke Medicine have taken a step toward understanding how to regenerate the connective tissue. By adding a chemical to cartilage cells, the chemical ...

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