News tagged with cell apoptosis
Scientists show how nerve wiring self-destructs
Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the ...
Neuroscience
May 09, 2013 |
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Fusion and cell death in the development of skeletal muscle
(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its proper ...
Medical research
Apr 26, 2013 |
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Fractalkine: New protein target for controlling diabetes
Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release ...
Diabetes
Apr 11, 2013 |
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New model may help predict response to chemotherapy for colorectal cancer
Scientists may be able to better predict which patients with colorectal cancer will respond to chemotherapy using a new mathematical model that measures the amount of stress required for a cancer cell to die without harming ...
Cancer
Jan 17, 2013 |
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Hard-to-treat Myc-driven cancers may be susceptible to drug already used in clinic
Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers ...
Cancer
Dec 14, 2012 |
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Researchers show Myc protein is cancer's 'volume control'
(Medical Xpress)—A protein called Myc, commonly found at high levels inside cancer cells, fuels the disease by allowing cells to override their in-built self-destruct mechanisms, according to two new studies by US scientists.
Cancer
Oct 01, 2012 |
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Hopes that new substance will induce cancer cell suicide
(Medical Xpress)—The p53 gene plays a key role in the prevention of cancer, by blocking cell growth and triggering programmed cell death or apoptosis. If, however, p53 has mutated and become defective, the cancer cells ...
Cancer
Sep 18, 2012 |
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Plant-based compound slows breast cancer in a mouse model
The natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumors in a mouse model with similarities to human breast cancer progression, according to a study published August 2 in the Journal of ...
Cancer
Aug 02, 2012 |
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Why smoking is 'BAD' for the Fallopian tube -- and increases the risk of ectopic pregnancy
Cigarette smoke reduces the production of a Fallopian tube gene known as "BAD", which helps explain the link between smoking and ectopic pregnancy. The finding, from scientists led by Drs Andrew Horne and Colin Duncan at ...
Health
Jul 03, 2012 |
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Mechanism ID'd for benefit of stem cells in autoimmunity
(HealthDay) -- Bone marrow mesenchymal stem cells (BMMSCs) activate a mechanism involving coupling of FAS/FAS ligand to induce T cell apoptosis and immune tolerance, according to an experimental study published ...
Medical research
May 02, 2012 |
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Scientists illuminate cancer cells' survival strategy
A team led by scientists at The Scripps Research Institute has discovered key elements of a strategy commonly used by tumor cells to survive when they spread to distant organs. The finding could lead to drugs that could inhibit ...
Cancer
Jan 26, 2012 |
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Possible new pathway can overcome glioblastoma resistance
Glioblastoma, a lethal brain cancer, is one of the most resistant to available therapies and patients typically live approximately 15 months.
Cancer
Jan 24, 2012 |
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Scientists identify cell death pathway involved in lethal sepsis
Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Sepsis is linked with massive cell death; however, the specific mechanisms involved in the lethality of sepsis are unclear. ...
Medical research
Dec 22, 2011 |
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A gene that protects against colorectal cancers
The research team in France has developed an animal model carrying a mutation of the DCC gene. Mice carrying the mutation develop tumours, because this gene can no longer induce the death of the cancer cells. This discovery ...
Cancer
Dec 14, 2011 |
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Research predicts how cancers will respond to chemo, rewrites old theory of why chemo works
Challenging a half-century-old theory about why chemotherapy agents target cancer, scientists at Dana-Farber Cancer Institute have devised a test that can predict how effective the drugs will be by determining whether a patient's ...
Cancer
Oct 27, 2011 |
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