Molecular switch identified that controls key cellular process
The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.
Medical research
Aug 01, 2012 |
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Demystifying the immortality of cancer cells
(Medical Xpress) -- In cancer cells, normal mechanisms governing the cellular life cycle have gone haywire. Cancer cells continue to divide indefinitely, without ever dying off, thus creating rapidly growing ...
Cancer
Jul 05, 2012 |
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Stopping and starting cancer cell cycle weakens and defeats multiple myeloma
Weill Cornell Medical College researchers have devised an innovative boxer-like strategy, based on the serial use of two anti-cancer drugs, to deliver a one-two punch to first weaken the defenses of multiple myeloma and then ...
Cancer
Jun 21, 2012 |
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Researchers uncover new clues about the origin of cancer
A study by Travis H. Stracker, researcher at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with scientists at the Memorial Sloan Kettering Cancer Center (MSKCC) in New York, reveals ...
Cancer
Jun 06, 2012 |
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Energy levels link sleep control mechanisms
Sleep, or lack of it, can determine level of cognitive performance which is linked with accidents as well as increased risk of serious health problems. Links between cell energy levels, gene transcription ...
Medical research
May 25, 2012 |
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Elimination of two ribosome subunits activates cell cycle control
Alterations in the formation of ribosomes (the elements of the cell where proteins are made) cause the induction of p53 protein and cell cycle disruption. This process is crucial to understand fundamental biological processes ...
Genetics
May 22, 2012 |
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Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
The American Cancer Society estimates that 44,000 new cases of pancreatic cancer will be diagnosed this year and that 37,000 people will die from the disease. These are not strong odds. A new drug, rigosertib, allows pancreatic ...
Cancer
Mar 02, 2012 |
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Slamming the brakes on the malaria life cycle
Scientists have discovered a new target in their fight against the devastating global disease 'malaria' thanks to the discovery of a new protein involved in the parasite's life cycle.
Medical research
Feb 23, 2012 |
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Short fasting cycles work as well as chemotherapy in mice
Man may not live by bread alone, but cancer in animals appears less resilient, judging by a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.
Cancer
Feb 08, 2012 |
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Mutated Kras spins a molecular loop that launches pancreatic cancer
Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms ...
Cancer
Jan 26, 2012 |
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Blood protein EPO involved in origin and spread of cancer
Researchers at the Swedish medical university Karolinska Institutet have demonstrated that a growth hormone, PDGF-BB, and the blood protein EPO are involved in the development of cancer tumours and that they combine to help ...
Cancer
Dec 05, 2011 |
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Scientists defeat hurdle to eradicating inactive multiple myeloma cells
Researchers at Virginia Commonwealth University Massey Cancer Center have developed a novel treatment strategy for multiple myeloma that delivers a deadly one-two blow to kill even the most inactive, or cytokinetically quiescent, ...
Cancer
Nov 14, 2011 |
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Pioneering IVF doctor dies in Australia
A pioneering Australian doctor known for his groundbreaking work on the world's first pregnancy through in vitro fertilisation (IVF) has died after a long illness.
Other
Sep 27, 2011 |
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Scientists uncover why the human heart can't regenerate itself
Stem cell researchers at UCLA have uncovered for the first time why adult human cardiac myocytes have lost their ability to proliferate, perhaps explaining why the human heart has little regenerative capacity.
Medical research
Aug 09, 2011 |
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Weakness in aging tied to leaky muscles
There is a reason exercise becomes more difficult with age. A report in the August Cell Metabolism, a Cell Press publication, ties the weakness of aging to leaky calcium channels inside muscle cells. But there is some good n ...
Medical research
Aug 02, 2011 |
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