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A genetic variation common in East Asian populations has been linked to cancer drug resistance

Tyrosine kinase inhibitors (TKIs) kill cancerous cells by inducing programmed cell death. They are of enormous therapeutic benefit to patients with chronic myeloid leukemia (CML) and certain types of lung ...

Genetics created Aug 02, 2012 | popularity not rated yet | comments 0

New biomarker for common lung cancer predicts responses to chemotherapy

Patients with the most common type of lung cancer are notoriously insensitive to chemotherapy drugs, including cisplatin. New findings related to the cellular pathways that regulate responses to cisplatin have now been published ...

Cancer created Jul 26, 2012 | popularity not rated yet | comments 0

Sickle cell trait can cause sudden cardiac death in black athletes: Why is this controversial?

While some published research has hinted at the connection between the sickle cell trait and sudden cardiac death among young, athletic African-American males, which was initially observed in black military recruits 25 years ...

Cardiology created Jul 25, 2012 | popularity not rated yet | comments 0

New biomarker in the blood may help predict Alzheimer's disease

Higher levels of a certain fat in the blood called ceramides may increase a person's risk of developing Alzheimer's disease, according to a study published in the July 18, 2012, online issue of Neurology.

Alzheimer's disease & dementia created Jul 18, 2012 | popularity not rated yet | comments 0

Small molecule may play big role in Alzheimer's disease

Alzheimer's disease is one of the most dreaded and debilitating illnesses one can develop. Currently, the disease afflicts 6.5 million Americans and the Alzheimer's Association projects it to increase to between ...

Alzheimer's disease & dementia created Jul 09, 2012 | popularity 4.2 / 5 (5) | comments 1 | with audio podcast

Biomarker predicts chemo response for osteosarcoma

(Medical Xpress) -- Scientists have found that a protein expressed by some cancers is a good predictor of how the cancer will respond to standard chemotherapy for osteosarcoma, the most common bone cancer in children. Knowing ...

Cancer created Jul 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Why smoking is 'BAD' for the Fallopian tube -- and increases the risk of ectopic pregnancy

Cigarette smoke reduces the production of a Fallopian tube gene known as "BAD", which helps explain the link between smoking and ectopic pregnancy. The finding, from scientists led by Drs Andrew Horne and Colin Duncan at ...

Health created Jul 03, 2012 | popularity not rated yet | comments 0

In vitro study identifies potential combination therapy for breast cancer

A study conducted at Boston University School of Medicine (BUSM) demonstrates an effective combination therapy for breast cancer cells in vitro. The findings, published in the July 2012 issue of Anticancer Research, raise ...

Cancer created Jul 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

Hormone discovered that preserves insulin production and beta cell function in diabetes

(Medical Xpress) -- Researchers at Duke University Medical Center have found protective, anti-diabetic functions for a hormone that, like insulin, is produced by the islet cells of the pancreas. The new hormone was found ...

Medical research created Jul 02, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Single protein promotes resistance to widely used anti-estrogen drugs

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.

Cancer created Jul 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study shows most commonly mutated gene in cancer may have a role in stroke

The gene p53 is the most commonly mutated gene in cancer. p53 is dubbed the “guardian of the genome” because it blocks cells with damaged DNA from propagating and eventually becoming cancerous. However, new research ...

Genetics created Jun 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study examines the biology of tumor-derived microvesicles

A new paper by Crislyn D'Souza-Schorey, professor of biological sciences at the University of Notre Dame, discusses the biology of tumor-derived microvesicles and their clinical application as circulating biomarkers. Microvesicles ...

Cancer created Jun 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Unexpected discovery highlights new role for cell death regulator

An unexpected discovery of how the body controls cell death has revealed a potential new therapeutic target.

Medical research created Jun 14, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Reach2HD, a Phase II study in Huntington's disease, launched

The Huntington Study Group (HSG), under the leadership of Ray Dorsey, M.D. with Johns Hopkins Medical and Diana Rosas, M.D. with Massachusetts General Hospital, is conducting a clinical trial in Huntington's disease (HD) ...

Neuroscience created Jun 07, 2012 | popularity not rated yet | comments 0

Researchers uncover new clues about the origin of cancer

A study by Travis H. Stracker, researcher at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with scientists at the Memorial Sloan Kettering Cancer Center (MSKCC) in New York, reveals ...

Cancer created Jun 06, 2012 | popularity not rated yet | comments 0