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News tagged with cell death

Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...

Genetics created May 14, 2013 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target

In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...

Cancer created May 13, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Unleashing the watchdog protein

McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The ...

Parkinson's & Movement disorders created May 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists show how nerve wiring self-destructs

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the ...

Neuroscience created May 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Research reveals cancer-suppressing protein 'multitasks'

The understanding of how a powerful protein called p53 protects against cancer development has been upended by a discovery by Walter and Eliza Hall Institute researchers.

Cancer created May 09, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

MicroRNA cooperation mutes breast cancer oncogenes

A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot ...

Cancer created May 07, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers describe how breast cancer cells acquire drug resistance

A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...

Cancer created May 07, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Team finds markers related to ovarian cancer survival and recurrence

(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 1 | with audio podcast

New light shed on early stage Alzheimer's disease

The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important ...

Alzheimer's disease & dementia created Apr 22, 2013 | popularity 5 / 5 (5) | comments 1 | with audio podcast

SUMO wrestling cells reveal new protective mechanism target for stroke

Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.

Medical research created 22 hours ago | popularity 5 / 5 (1) | comments 0

Individual efficacy of chemotherapies

The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Team finds melatonin delays ALS symptom onset and death in mice

Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new study by researchers at ...

Neuroscience created Apr 25, 2013 | popularity not rated yet | comments 0

Dopamine-producing neurons derived from bone marrow stem cells yield improvements in monkeys with Parkinson's disease

Parkinson's disease is a neurodegenerative disorder characterized by the death of dopamine-producing neurons in the midbrain, resulting in motor symptoms such as tremors and stiffness. The cause of cell death ...

Parkinson's & Movement disorders created Apr 22, 2013 | popularity 5 / 5 (1) | comments 0

Searching for therapeutic synergy in primary effusion lymphoma

Primary effusion lymphoma (PEL) is a rare, fatal form of aggressive B-cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). The disease most commonly occurs in immunocompromised patients, such as those with ...

Cancer created May 01, 2013 | popularity not rated yet | comments 0

Food dye could provide 'blueprint' for treatment of Panx1-related diseases

The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physi ...

Medical research created Apr 29, 2013 | popularity not rated yet | comments 0

Programmed cell death

Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.

For more information about Programmed cell death, read the full article at Wikipedia.
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