Study uncovers mechanism used by BRCA1 to suppress tumors
A new study by Georgetown University Medical Center researchers reveals how a well-known tumor suppressor gene may be functioning to stop cancer cell growth.
Cancer
Dec 17, 2012 |
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Scientists identify a new layer of complexity within colon cancer
Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumour cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal ...
Cancer
Dec 13, 2012 |
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MicroRNA-218 targets medulloblastoma, most aggressive childhood brain cancer
Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes ...
Cancer
Dec 13, 2012 |
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Researchers say effective immunotherapy for melanoma hinges on blocking suppressive factors
(Medical Xpress)—Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of myeloid-derived suppressor cells ...
Immunology
Dec 11, 2012 |
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Novel drug therapy targets aggressive form of non-Hodgkin's lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL ...
Cancer
Dec 10, 2012 |
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His and hers: Male hormones control differences in mammary gland nerve growth
Johns Hopkins scientists have found a surprising mechanism that gives male sex hormones like testosterone control over the gender-specific absence or presence of mammary gland nerves that sense the amount ...
Medical research
Dec 06, 2012 |
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Research on blood vessel proteins holds promise for controlling 'blood-brain barrier'
Working with mice, Johns Hopkins researchers have shed light on the activity of a protein pair found in cells that form the walls of blood vessels in the brain and retina, experiments that could lead to therapeutic ...
Medical research
Dec 06, 2012 |
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Breast cancer drug could hold the key to fighting other tumours
New research out of the United Kingdom is showing that a common drug used in the fight against breast cancer could also be employed in the fight against other tumours. The drug in question is geldanamycin, ...
Cancer
Dec 05, 2012 |
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Improving chemotherapy effectiveness by acting on the immune system
An Inserm team in Dijon directed by François Ghiringhelli is to publish an article this week in the Nature Medicine review. The article suggests that two chemotherapy drugs frequently used to treat digestive and breast cancers ...
Immunology
Dec 04, 2012 |
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Using unique combination of diet and radiation therapy, researchers successfully destroy brain tumor cells
A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy. The study, ...
Cancer
Dec 04, 2012 |
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Stem cell-derived dopaminergic neurons rescue motor defects in Parkinsonian monkeys
Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter ...
Parkinson's & Movement disorders
Dec 03, 2012 |
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Clinical trial hits new target in war on breast cancer
Breast cancers are defined by their drivers – estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer ...
Cancer
Dec 03, 2012 |
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Cometriq approved for rare thyroid cancer
(HealthDay)—Cometriq (cabozantinib) has been approved by the U.S. Food and Drug Administration to treat modullary thyroid cancer that has spread to other parts of the body, the agency said Thursday.
Medications
Nov 29, 2012 |
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Researchers identify gene involved in lung tumor growth
Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that ...
Cancer
Nov 29, 2012 |
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Scientists uncover a novel cooperative effort to stop cancer spread
(Medical Xpress)—Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the ...
Cancer
Nov 28, 2012 |
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