Northwestern Medicine scientists have identified how one gene connects glioblastoma stem cell self-renewal to microglia immunosuppression in glioblastoma, according to a new study published in Nature Immunology.
Sep 27, 2023
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Rapid wound healing remains a pressing clinical challenge, necessitating studies to hasten this process. A promising approach involves the utilization of human umbilical cord mesenchymal stem cells (hUC-MSCs) derived exosomes. ...
Sep 26, 2023
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Lung fibrosis is a debilitating disease affecting nearly 250,000 people in the U.S. alone with 50,000 new cases reported each year. There is currently no cure and limited available treatment options, underscoring the pressing ...
Sep 26, 2023
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Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors. However, ...
Sep 26, 2023
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Investigators led by Kathleen Green, Ph.D., the Joseph L. Mayberry, Sr., Professor of Pathology and Toxicology, have discovered novel intercellular "crosstalk" between epidermal keratinocytes and melanoma cells that promote ...
Sep 22, 2023
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Immunotherapy, which uses the body's own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it. Thus, cancer researchers are seeking new ways to optimize immunotherapy so ...
Sep 21, 2023
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Northwestern Medicine investigators have discovered how the protein PD-1 controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas (T-NHLs), according to a study published ...
Sep 21, 2023
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A new editorial paper titled "Potential repurposing of DPP4 inhibitors for target therapy resistance in renal cell carcinoma" has been published in Oncotarget.
Sep 20, 2023
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Investigators have discovered a novel molecular pathway that promotes tumor growth in uterine fibroids that contain a specific genetic mutation, which could inform the development of new targeted therapies, according to a ...
Sep 20, 2023
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Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The ...
Sep 18, 2023
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