When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...
Feb 28, 2024
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Head and neck squamous cell carcinoma (HNSCC) is a type of cancer that affects the mucous membranes of the mouth, nose, and throat. HNSCC is typically associated with tobacco exposure, alcohol abuse, and viral infections. ...
Feb 27, 2024
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Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study focusing on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the ...
Feb 27, 2024
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A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint ...
Feb 27, 2024
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Researchers at the Technion's Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy ...
Feb 26, 2024
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Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells. The journal Blood ...
Feb 26, 2024
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In an early-phase clinical trial, a combination of antibody-based medications targeting the immune system generated promising safety data and anti-tumor activity in individuals with various types of advanced cancer. The findings ...
Feb 26, 2024
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Siteman Cancer Center, based at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, is one of the first centers nationwide to offer a newly approved cell-based immunotherapy that targets melanoma.
Feb 24, 2024
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Vitamin B6 is beneficial in many ways, notably for its role in maintaining a strong immune system. However, when pancreatic cancer develops, its cells also need vitamin B6 to replicate. During the ensuing tug-of-war over ...
Feb 23, 2024
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In a significant breakthrough in inflammatory arthritis research, a study published today (Feb. 23) in Nature Immunology has revealed that inflammation-associated fibroblasts—a type of cell in connective tissues—can switch ...
Feb 23, 2024
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