Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic ...
Jan 5, 2024
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A team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification ...
Dec 21, 2023
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Resistance to therapies is one of the obstacles to overcome in cancer treatments. Understanding the mechanisms of this resistance is essential to design strategies that favor tumor cell death. A study led by the Protein Kinases ...
Dec 14, 2023
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Spinal muscular atrophy (SMA) is a devastating pediatric neuromuscular disorder caused by loss-of-function mutations in the SMN1 gene, which prevents the body from producing enough of the survival motor neuron (SMN) protein ...
Dec 7, 2023
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Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as effective in treating ...
Nov 30, 2023
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The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to findings of a new study from Gladstone Institutes.
Nov 27, 2023
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A team of researchers in China has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This "chimeric" monkey is composed of cells that originate ...
Nov 9, 2023
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Endometrial carcinoma, a cancer of the lining of the uterus, is the most common gynecologic malignancy in developed nations. Over the past decade, its incidence has steadily increased (approximately 1% annually) and mortality ...
Oct 12, 2023
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A biobank for all, in which a person from any background could find a bone marrow donor for a stem cell transplant, is a major goal for stem cell science. While repositories of cell lines that could be a match for most patients ...
Sep 28, 2023
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A team of biomedical engineers from Brown University has developed a new hydrogel-based delivery system that balances the acidic environment in a tumor and greatly enhances the cancer-fighting activity of the chemotherapeutic ...
Sep 20, 2023
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