Immunology

Cellular waste may supercharge immune cell function

The immune cells that protect us from infection and cancer seek out a wide array of fuel sources to power their function—including some long thought to be cellular waste products.

Oncology & Cancer

Researchers identify an Achilles' heel in neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN ...

Oncology & Cancer

New understanding of how faulty metabolism triggers adrenal cancer

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...

Medical research

New target identified for treatment of premature aging disease

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered. ...

Oncology & Cancer

Cool room temperature inhibited cancer growth in mice

Turning down the thermostat seems to make it harder for cancer cells to grow, according to a study in mice by researchers at Karolinska Institutet in Sweden. The study, published in the journal Nature, found that chilly temperatures ...

Oncology & Cancer

Leukemia vulnerability discovered causing drug sensitivity

All human tumors originating from various tissues share a series of properties that define them, including the ability to prevent cell death. Instead, healthy organs induce programmed cell death or apoptosis to balance their ...

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