In Alzheimer's disease and related dementias, cognitive decline is driven by the over-accumulation of a normal brain protein known as tau. Wherever tau builds up, nearby brain tissue starts to degenerate and die.
Nov 22, 2023
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It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism—the intrinsic link between metabolism in immune cells and their immune function. ...
Nov 20, 2023
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Gene therapy has great promise for treating genetic diseases, and even for more common diseases such as atherosclerosis (hardening of the arteries). Over the past decade, the gene-editing technology CRISPR (Clustered Regularly ...
Nov 16, 2023
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Canadian scientists have established for the first time a new mechanism and role for LDL in the development of type 2 diabetes, beyond its traditional role in the development of cardiovascular disease in humans.
Nov 13, 2023
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A group of researchers led by the Francis Crick Institute, working with the National Physical Laboratory (NPL) and Imperial College London, have discovered that breast cancer cells expressing a cancer-driving gene heavily ...
Nov 9, 2023
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Type 1 diabetes is an autoimmune disease that causes the body's immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing ...
Nov 2, 2023
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The development of the brain requires an elaborate, tightly organized chain of events that are jumpstarted by neural stem cells, which give rise to increasingly specialized cells that carry out all brain functions. But what ...
Oct 26, 2023
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A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.
Oct 9, 2023
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Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote ...
Oct 6, 2023
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Researchers at University of California San Diego School of Medicine and the Salk Institute for Biological Studies have created a unique, cell-by-cell atlas of the amygdala, a small structure deep within the brain that plays ...
Oct 5, 2023
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