Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer ...
Genetics
Jan 10, 2013 |
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Potential stem cell therapy for diabetes: Study looks at differentiation of hESCs in endocrine cell progression
Type 1 and type 2 diabetes results when beta cells in the pancreas fail to produce enough insulin, the hormone that regulates blood sugar. One approach to treating diabetes is to stimulate regeneration of ...
Medical research
Jan 10, 2013 |
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Study shows that human hearts generate new cells after birth
Researchers at Boston Children's Hospital have found, for the first time that young humans (infants, children and adolescents) are capable of generating new heart muscle cells. These findings refute the long-held belief that ...
Medical research
Jan 10, 2013 |
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Genes and obesity: Fast food isn't only culprit in expanding waistlines—DNA is also to blame
Researchers at UCLA say it's not just what you eat that makes those pants tighter—it's also genetics. In a new study, scientists discovered that body-fat responses to a typical fast-food diet are determined in large part ...
Medical research
Jan 08, 2013 |
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Sickle cell disease, sickle cell trait are not the same
(HealthDay)—Both sickle cell disease and the condition known as sickle cell trait are genetic blood diseases: You're born with one or the other because of the genes inherited from your parents. Beyond that, the two conditions ...
Diseases, Conditions, Syndromes
Dec 28, 2012 |
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Staphylococcus aureus: Why it just gets up your nose
A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. au ...
Diseases, Conditions, Syndromes
Dec 27, 2012 |
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Identification of developmental 'master switch' helps scientists explore function of infection-preventing cells
Every bite of food or drink of water is an invitation for potentially harmful bacteria and viruses to set up shop in the body. In order to protect against such invaders, the mucous membrane that lines the ...
Immunology
Dec 14, 2012 |
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Breakthrough research discovery to help heal chronic wounds
(Medical Xpress)—The University of Queensland researchers have successfully restored wound healing in a model of diabetes paving the way for new treatments for chronic wounds.
Medical research
Dec 14, 2012 |
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A key gene for brain development
(Medical Xpress)—Neurobiologists at the Research institute of Molecular Pathology (IMP) in Vienna have discovered one of the key genes required to make a brain. Mutations in this gene, called TUBB5, cause ...
Genetics
Dec 14, 2012 |
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Despite cART, anal cancer risk still high for HIV-infected
(HealthDay)—For HIV-infected patients, despite combined antiretroviral treatment (cART), the risk of anal cancer is still much higher than in the general population, according to a study published in the ...
HIV & AIDS
Dec 13, 2012 |
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Different genes behind same adaptation to thin air
Highlanders in Tibet and Ethiopia share a biological adaptation that enables them to thrive in the low oxygen of high altitudes, but the ability to pass on the trait appears to be linked to different genes in the two groups, ...
Medical research
Dec 06, 2012 |
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Longer life expectancy, aging population necessitate new strategies for prostate cancer care
The population of the United States is getting older, due not only to aging boomers but also to a four-year increase in life expectancy from 1990 to 2010. An aging population means increased diagnosis of prostate cancer. ...
Cancer
Dec 04, 2012 |
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ALS TDI and Gladstone Institutes collaborate to discover potential ALS treatments
The ALS Therapy Development Institute (ALS TDI) and the Gladstone Institutes today announced the formation of a research collaboration to speed the discovery of potential treatments for ALS through the preclinical drug development ...
Medical research
Dec 04, 2012 |
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Managing cellular security systems
Conventional dendritic cells (cDCs) are the immune system's patrol. They recognize foreign threats and trigger a defensive response, while restraining immune reactions against inappropriate targets like host ...
Medical research
Nov 30, 2012 |
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Molecular root of 'exhausted' T cells in chronic viral infection
When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system ...
Medical research
Nov 29, 2012 |
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