Oncology & Cancer

CDK4: A master regulator of the cell cycle and its role in cancer

The mammalian cell cycle is divided into four phases, Gap 1 (G1), Synthesis (S), Gap 2 (G2) and Mitosis (M), whose order and timing are critical for accurate transmission of genetic information. Consequently, a number of ...

Oncology & Cancer

Indirectly influencing cancer's out-of-control cell replication

As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...

Genetics

New insights into lithium's effectiveness for bipolar disorder

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics. About half of patients respond very well to lithium salts ...

Oncology & Cancer

A new drug target for triple-negative breast cancer

Research led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans' Schools of Medicine and Graduate Studies, reports a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy ...

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