News tagged with cell proliferation
Related topics: cancer cells , breast cancer , cancer , tumor growth , stem cells
Key enzyme plays roles as both friend and foe to cancer
A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of ...
Medical research
Jun 14, 2012 |
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Japanese scientists show 'new' liver generation using hepatocyte cell transplantation
Researchers in Japan have found that hepatocytes, cells comprising the main tissue of the liver and involved in protein synthesis and storage, can assist in tissue engineering and create a "new liver system" in mouse models ...
Medical research
Jun 11, 2012 |
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Normal gene hinders breast cancer chemotherapy
Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective. The preclinical study led by MD Anderson scientists was published today in the ...
Cancer
Jun 11, 2012 |
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Probing the mechanism of ADAM28-mediated cancer metastasis
ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives ...
Cancer
Jun 08, 2012 |
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Cancer may require simpler genetic mutations than previously thought
Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute ...
Cancer
May 25, 2012 |
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Amino acid consumption associated with how fast cancer cells divide
For almost a century, researchers have known that cancer cells have peculiar appetites, devouring glucose in ways that normal cells do not. But glucose uptake may tell only part of cancer's metabolic story. Researchers from ...
Cancer
May 24, 2012 |
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Inhibition of PBEF is a possible therapeutic target for pulmonary hypertension
Inhibition of pre-B Cell Colony-Enhancing Factor (PBEF) could be a potential therapeutic target for pulmonary hypertension (PH), according to a preclinical study in an animal model of PH.
Diseases, Conditions, Syndromes
May 22, 2012 |
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Breast cancer effectively treated with chemical found in celery
Apigenin, a natural substance found in grocery store produce aisles, shows promise as a non-toxic treatment for an aggressive form of human breast cancer, following a new study at the University of Missouri. MU researchers ...
Cancer
May 16, 2012 |
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Drug kills cancer cells by restoring faulty tumor suppressor
A new study describes a compound that selectively kills cancer cells by restoring the structure and function of one of the most commonly mutated proteins in human cancer, the "tumor suppressor" p53. The research, published ...
Cancer
May 14, 2012 |
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Molecule found that inhibits estrogen, key risk factor for endometrial and breast cancers
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a molecule that inhibits the action of estrogen. This female hormone plays a key role in the growth, maintenance and repair of reproductive ...
Medical research
May 09, 2012 |
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Immune-response genes affecting breast tumor eradication
Breast cancer patients whose tumors express high levels of genes related to immune response are more likely to have their tumor completely eradicated by pre-operative chemotherapy compared to patients with low expression ...
Cancer
May 03, 2012 |
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Growing up as a neural stem cell: The importance of clinging together and then letting go
Can one feel too attached? Does one need to let go to mature? Neural stem cells have this problem, too.
Neuroscience
Apr 25, 2012 |
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Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor
St. Jude Children's Research Hospital scientists have rewritten the job description of the protein TopBP1 after demonstrating that it guards early brain cells from DNA damage. Such damage might foreshadow later problems, ...
Neuroscience
Apr 23, 2012 |
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New genetic mechanism of immune deficiency discovered
Researchers at National Jewish Health have discovered a novel genetic mechanism of immune deficiency. Magdalena M. Gorska, MD, PhD, and Rafeul Alam, MD, PhD, identified a mutation in Unc119 that causes immunodeficiency known ...
Immunology
Apr 20, 2012 |
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Two repressor genes identified as essential for placental development
Two particular repressor genes in a family of regulatory genes are vital for controlling cell proliferation during development of the placenta, according to a new study by researchers with the Ohio State University Comprehensive ...
Genetics
Apr 16, 2012 |
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