Neuroscience
Significant step on path to developing Alzheimer's therapy
A brain protein with high potential to delay or reverse the onset of Alzheimer's disease has been exploited by University of Otago researchers.
Aug 1, 2022
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News tagged with cell proliferation
Medications
Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation
Worldwide, breast cancer (BC) is the second most common cancer. Pharmacologically targeting cyclin-dependent kinase 4 and 6 (CDK4 & 6) has proven to be a successful therapeutic approach in patients with estrogen receptor-positive ...
Jul 6, 2022
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Cardiology
Changed gene expression after heart surgery extends cardiomyocyte regeneration
While lower vertebrates can repair their adult hearts after a heart attack, mammals—including humans—cannot. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few days after birth because ...
Jun 24, 2022
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Oncology & Cancer
Genome-wide intricacies of cancer inhibitor untangled
A newly discovered inhibitor of a common cancer-causing protein operates selectively, reducing expression of genes that fuel rampant cell proliferation and alter the epigenome, according to a Northwestern Medicine study published ...
Jun 6, 2022
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Immunology
Scientists solve long-standing mystery: Why do some asthma patients respond poorly to treatment?
When taking medicine during an asthma attack, patients with the most severe form of asthma produce in their airways special substances that block the treatment from working, according to a study where Rutgers scientists collaborated ...
May 30, 2022
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Medical research
Two new studies yield clues to the metabolic mysteries of why some cancers grow out of control and spread
Researchers working in a U of A laboratory have uncovered two previously unknown ways that metabolism triggers cancer cell growth, uncovering potential new pathways for diagnosis and treatment.
May 5, 2022
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Diabetes
Safer mass production of endocrine cells for stem cell-derived therapy for diabetes
The transplantation of islet-like endocrine cells derived from human pluripotent stem cells, such as ES cells and iPS cells, is expected to be a curative treatment for diabetes. Producing the islet-like endocrine cells artificially ...
Apr 15, 2022
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Medical research
Researchers develop method to advance maturation of human pluripotent stem cell-derived heart cells
A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)—cells that support heart muscle contraction, generated in the ...
Apr 7, 2022
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Oncology & Cancer
New gene targets for treating adult blood cancer
Hokkaido University scientists have identified new targets for treating an aggressive form of adult leukemia with existing drugs. The findings were published in the journal Blood.
Mar 31, 2022
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Neuroscience
Oleic acid, a key to activating the brain's 'fountain of youth'
Many people dread experiencing the cognitive and mood declines that often accompany reaching an advanced age, including memory disorders such as Alzheimer's disease and mood conditions like depression. While searching for ...
Mar 22, 2022
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