TIM and TAM: 2 paths used by the Dengue virus to penetrate cells
By demonstrating that it is possible to inhibit the viral infection in vitro by blocking the bonding between the virus and these receptors, the researchers have opened the way to a new antiviral strategy. These works were ...
Diseases, Conditions, Syndromes
Oct 23, 2012 |
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Immune cells make flexible choices
Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats ...
Immunology
Oct 22, 2012 |
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Study clarifies process controlling night vision
On the road at night or on a tennis court at dusk, the eye can be deceived. Vision is not as sharp as in the light of day, and detecting a bicyclist on the road or a careening tennis ball can be tough.
Neuroscience
Oct 17, 2012 |
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Painless skin rash predicts survival benefit from latest lung cancer drug, study finds
(Medical Xpress)—Elderly patients with advanced non small cell lung cancer (NSCLC) who developed a rash within 28 days of receiving the targeted drug erlotinib (Tarceva) survived on average 6.2 months, c ...
Cancer
Oct 17, 2012 |
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Scientists provide detailed view of brain protein structure: Results may help improve drugs for neurological disorders
Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Medical research
Oct 10, 2012 |
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Bitter taste receptors regulate the upper respiratory defense system, research shows
A new study from a team of researchers at the Perelman School of Medicine at the University of Pennsylvania, the Monell Chemical Senses Center, and the Philadelphia VA Medical Center, reveals that a person's ability to taste ...
Medical research
Oct 08, 2012 |
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Inappropriate activation of an immune signaling pathway during infection leaves the body vulnerable to sepsis
The inflammatory response is a double-edged sword—it enables the body to mount a vigorous defense against infection, but can also inflict serious physiological damage if allowed to rampage uncontrolled. ...
Immunology
Sep 26, 2012 |
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LIFR protein suppresses breast cancer metastasis
A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texas MD Anderson Cancer ...
Cancer
Sep 25, 2012 |
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Excitotoxicity and nerve cell death
Neural excitotoxicity can be involved in spinal cord injury, traumatic hearing loss and Alzheimer's. The Stressprotect project has gathered data on this often devastating phenomenon at biochemical, genomic ...
Medical research
Sep 25, 2012 |
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Scientists reverse Alzheimer's-like memory loss in animal models by blocking EGFR signaling
A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness ...
Alzheimer's disease & dementia
Sep 24, 2012 |
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Like prostate cancer, bladder cancer patients may benefit from anti-androgen therapy
Bladder cancer patients whose tumors express high levels of the protein CD24 have worse prognoses than patients with lower CD24. A University of Colorado Cancer Center study published today in the Proceedings of the National Ac ...
Cancer
Sep 24, 2012 |
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Biomarkers for antidepressant treatment response
(Medical Xpress)—Researchers from King's College London's Institute of Psychiatry (IoP) have identified new biomarkers for antidepressant treatment response, an important step towards developing personalised ...
Psychology & Psychiatry
Sep 20, 2012 |
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Fighting melanoma's attraction to the brain
(Medical Xpress)—The process of metastasis, by which cancer cells travel from a tumor site and proliferate at other sites in the body, is a serious threat to cancer patients. According to the National Cancer ...
Cancer
Sep 19, 2012 |
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Researchers identify gene partly responsible for maternal care in mice
(Medical Xpress)—The medial preoptic area of the brain has been found over the years to be very closely involved with certain behaviors in mice, such as sexual proclivity, locomotion, aggression and the ...
Genetics
Sep 18, 2012 |
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Researchers reveal underlying mechanism of powerful chemotherapy for prostate cancer treatment
The power of taxane-based chemotherapy drugs are misunderstood and potentially underestimated, according to researchers at Weill Cornell Medical College in the September 15 issue of the journal Cancer Research.
Cancer
Sep 17, 2012 |
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