Scientists have solved a long-standing mystery surrounding a cancer-promoting protein and how it causes tumor growth. The findings are an important step in the quest to make cancer drugs more effective since aggressive tumors ...
Oct 12, 2022
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Pancreatic ductal adenocarcinoma (PDAC) is the most common and most lethal form of pancreatic cancer. The overall 5-year survival for patients with PDAC is just 7.1 percent.
Oct 6, 2022
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Every cell has two mechanisms for repairing DNA single- or double-strand breaks, which can be induced by such factors as environmental toxins, chemotherapy, or ionizing radiation. The first one consists of the DNA repair ...
Sep 21, 2022
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Natural killer (NK) cells have lately become a hot focus of efforts to develop new immunotherapies. Researchers led by Ludwig Harvard's Tony Letai, whose team collaborated closely with the Ludwig Harvard Kai Wucherpfennig ...
Sep 20, 2022
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The exchange of gases between the air we breathe and our blood takes place via alveoli—tiny air sacs in our lungs. For this process to run smoothly, the epithelial cells of the alveoli produce a substance called "surfactant" ...
Sep 16, 2022
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134
If bacteria enter the body, it often takes just a few minutes for the innate immune system to recognize them as foreign and set the immune defense in motion. Receptors of the immune system that recognize bacterial cell wall ...
Aug 25, 2022
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The immune system can become the enemy when mechanisms that are actually protective get out of control. In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages that can be fatal if left ...
Aug 24, 2022
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In a small patch of skin no bigger than an inch, there are millions of cells all performing duties, like protecting us from bacteria and sensing temperature. A portion of them are melanocytes, a type of cell dedicated to ...
Aug 4, 2022
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Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.
Jul 28, 2022
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Bone remodeling in the body involves a balancing act between osteoblasts, cells that build bone, and osteoclasts, cells that break it down. Diseases such as osteoporosis, arthritis, and periodontitis involve bone loss, and ...
Jul 26, 2022
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