News tagged with cell surface

Related topics: cells · immune response · cancer cells · protein

Scientists identify new approach for treating skin cancer

Using new and innovative immune-therapeutic approaches to silence "don't eat me" signaling proteins recognized by specialized cells of the immune system, University of California, Irvine molecular biologists and their colleagues ...

Aug 01, 2016
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Regulation of semiochemicals in inflammation

Tumour necrosis factor-alpha (TNF-α) is a central signalling substance of the immune system and involved in many inflammatory processes. Blocking this molecule is the foundation of modern treatment against inflammatory diseases ...

Jun 02, 2016
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Sticky molecules to tackle obesity and diabetes

Okayama University researchers report that the over-expression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal ...

May 09, 2016
popularity15 comments 0

Receptor (biochemistry)

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.

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