News tagged with cell surface receptor
New therapy holds promise for aggressive breast cancers
Australian researchers have developed a new therapy to treat a common and aggressive form of breast cancer and stop the disease spreading, with a 100% success rate reported in mice.
Cancer
Apr 16, 2013 |
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A hijacking of healthy cellular circuits
Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Cancer
Apr 08, 2013 |
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Cellular gatekeepers do more than open doors for drugs, study finds
(Medical Xpress)—The cellular gatekeepers that escort the most common pharmaceuticals into our cells continue to work within the cells as well, according to a UC San Francisco discovery that could transform drug design ...
Medical research
Apr 08, 2013 |
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How the immune system positions its gatekeepers
(Medical Xpress)—For an immune response to get underway, an invading microbe must first be halted in the spleen, and then digested by immune cells known as 'dendritic cells', which guard specific portals. ...
Immunology
Mar 19, 2013 |
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Gene discovery reveals importance of eating your greens
(Medical Xpress)—Eating your greens may be even more important that previously thought, with the discovery that an immune cell population essential for intestinal health could be controlled by leafy greens ...
Immunology
Mar 04, 2013 |
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New details on the molecular machinery of cancer
Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor ...
Cancer
Feb 11, 2013 |
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Green tea and red wine extracts interrupt Alzheimer's disease pathway in cells
Natural chemicals found in green tea and red wine may disrupt a key step of the Alzheimer's disease pathway, according to new research from the University of Leeds.
Alzheimer's disease & dementia
Feb 05, 2013 |
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Study shows how immune cells navigate through the skin by sensing graded patterns of immobilized directional cues
A research paper by the group of Michael Sixt, Assistant Professor at the Institute of Science and Technology Austria (IST Austria), published today in Science, provides new insights into how immune cells ...
Medical research
Jan 17, 2013 |
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Promising new finding for therapies to treat persistent seizures in epileptic patients
In a promising finding for epileptic patients suffering from persistent seizures known as status epilepticus, researchers reported today that new medication could help halt these devastating seizures. To ...
Neuroscience
Jan 16, 2013 |
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Scientists find a new way to boost common cancer drugs
Shutting down a specific pathway in cancer cells appears to improve the ability of common drugs to wipe those cells out, according to new research from scientists at Fox Chase Cancer Center, published in the January issue ...
Cancer
Jan 14, 2013 |
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Study identifies potential new pathway for drug development
A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a ...
Medical research
Dec 10, 2012 |
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New hope for setback-dogged cancer treatment
Several drugs companies have ineffectively tried to produce antibodies that bind to the IGF-1 receptor on the cell surface, which has a critical part to play in the development of cancer. Scientists at Karolinska Institutet ...
Cancer
Nov 26, 2012 |
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Inappropriate activation of an immune signaling pathway during infection leaves the body vulnerable to sepsis
The inflammatory response is a double-edged sword—it enables the body to mount a vigorous defense against infection, but can also inflict serious physiological damage if allowed to rampage uncontrolled. ...
Immunology
Sep 26, 2012 |
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Are cold feet plaguing your relationship? Physiologists identified biological mechanism that could be responsible
Cold feet -- those chilly appendages that plague many people in the winter and an unlucky few all year round -- can be the bane of existence for singles and couples alike. In a new study, scientists led by Selvi C. Jeyaraj ...
Medical research
Jul 31, 2012 |
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Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved
Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells.
Cancer
May 30, 2012 |
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