News tagged with cell surface

Related topics: cells · immune response · cancer cells · protein

Why tumors evade immunotherapy

Immunotherapy is a new and highly promising form of treatment for cancer. In many patients, however, tumors recur after immunotherapy. In the latest issue of the Journal of Experimental Medicine, the members of a research ...

Oct 06, 2016
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Scientists identify new approach for treating skin cancer

Using new and innovative immune-therapeutic approaches to silence "don't eat me" signaling proteins recognized by specialized cells of the immune system, University of California, Irvine molecular biologists and their colleagues ...

Aug 01, 2016
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Regulation of semiochemicals in inflammation

Tumour necrosis factor-alpha (TNF-α) is a central signalling substance of the immune system and involved in many inflammatory processes. Blocking this molecule is the foundation of modern treatment against inflammatory diseases ...

Jun 02, 2016
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Receptor (biochemistry)

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.

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