Mutated Kras spins a molecular loop that launches pancreatic cancer
Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms ...
Cancer
Jan 26, 2012 |
5 / 5 (1) |
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High risk oesophageal cancer gene discovered
New research from Queen Mary, University of London has uncovered a gene which plays a key role in the development of oesophageal cancer (cancer of the gullet).
Genetics
Jan 19, 2012 |
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Drug improves survival of colorectal cancer patients, trial results show
An investigational drug called regorafenib slowed the progression of tumors and lengthened the lives of patients with metastatic colorectal cancer, an international phase III clinical trial found. The findings were presented ...
Cancer
Jan 18, 2012 |
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Breakthrough in early cancer detection
Cape Cod-TV correspondent Melissa Chartrand went into the hospital three years ago to undergo a hysterectomy, a common procedure that was supposed to eliminate her abdominal pains. But for Melissa, a far more serious pain ...
Cancer
Jan 10, 2012 |
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Scientists find genetic key to why some cancer patients don't respond to treatment
(Medical Xpress) -- Researchers from Newcastle University have identified a gene variation carried by 20% of the population which can significantly affect how patients with a rare type of blood cancer will respond to treatment.
Cancer
Jan 05, 2012 |
5 / 5 (2) |
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Cleveland Clinic researcher discovers genetic cause of thyroid cancer
Cleveland Clinic researchers have discovered three genes that increase the risk of thyroid cancer, which is has the largest incidence increase in cancers among both men and women.
Cancer
Dec 23, 2011 |
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Researchers identify potential target to delay metastatic pancreatic cancer and prolong survival
Often, and without much warning, pancreatic cancer cells slip through the endothelial cells, head into the blood and out to other parts of the body to metastasize, making it one of the deadliest and hardest to treat cancers ...
Cancer
Dec 21, 2011 |
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Grafting of human spinal stem cells into ALS rats best with immunosuppressant combination
A team of researchers grafting human spinal stem cells into rats modeled with amyotrophic lateral sclerosis (ALS), also known as "Lou Gehrig's Disease," a degenerative, lethal, neuromuscular disease, have tested four different ...
Medical research
Dec 19, 2011 |
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When standard treatment fails: Jefferson to start unique immunotherapy for brain tumor patients
Physicians at the Jefferson Hospital for Neuroscience (JHN), the region's only dedicated hospital, are tackling a particularly aggressive brain cancer that even surgery, chemotherapy and radiation often fail to treat with ...
Cancer
Dec 14, 2011 |
5 / 5 (2) |
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A gene that protects against colorectal cancers
The research team in France has developed an animal model carrying a mutation of the DCC gene. Mice carrying the mutation develop tumours, because this gene can no longer induce the death of the cancer cells. This discovery ...
Cancer
Dec 14, 2011 |
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Obesity and diabetes epidemics spur increase in nonalcoholic steatohepatitis
Nonalcoholic steatohepatitis (NASH) occurs when fat builds up in the liver. This accumulation of fat damages the liver and leads to cirrhosis. NASH is rapidly increasing in the U.S. mainly related to the epidemics of obesity ...
Diseases, Conditions, Syndromes
Dec 14, 2011 |
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Bone marrow and blood stem cell transplant survival rates equal, when donor is unrelated to patient
Patients who receive a blood stem cell transplant from a donor outside of their family to treat leukemia and other blood diseases are more likely to have graft failure but less likely to experience graft-versus-host disease, ...
Medical research
Dec 12, 2011 |
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Novel experimental agent is highly active in CLL patients, interim study shows
An interim analysis of a phase Ib/II clinical trial indicates that a novel experimental agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other ...
Cancer
Dec 11, 2011 |
3.5 / 5 (2) |
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Scientists discover how to beat resistance to standard leukaemia drug
(Medical Xpress) -- Cancer Research UK-funded scientists at The Institute of Cancer Research (ICR) have revealed a technique to kill chronic myeloid leukaemia (CML) cells that have stopped responding to a targeted drug, according ...
Cancer
Dec 09, 2011 |
5 / 5 (1) |
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Long non-coding RNA prevents the death of maturing red blood cells
A long non-coding RNA (lncRNA) regulates programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. This is the first time a lncRNA has been found ...
Genetics
Dec 07, 2011 |
5 / 5 (1) |
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