Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread
An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells ...
Cancer
May 07, 2013 |
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Scientists find potential therapeutic target for Cushing's disease
Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Cholesterol drugs might boost kidney cancer survival
(HealthDay)—Cholesterol-lowering statin drugs that are taken by millions of Americans might also improve survival from a type of kidney cancer called renal cell carcinoma, a new study suggests.
Cancer
May 07, 2013 |
5 / 5 (1) |
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MicroRNA cooperation mutes breast cancer oncogenes
A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot ...
Cancer
May 07, 2013 |
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Researchers describe how breast cancer cells acquire drug resistance
A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...
Cancer
May 07, 2013 |
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Restless legs syndrome, insomnia and brain chemistry: A tangled mystery solved?
Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge ...
Neuroscience
May 07, 2013 |
4.4 / 5 (5) |
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Discovery of new hormone opens doors to new type 2 diabetes treatments
Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...
Diabetes
May 07, 2013 |
4.6 / 5 (8) |
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Type 1 diabetes and heart disease linked by inflammatory protein
Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...
Inflammatory disorders
May 07, 2013 |
4.5 / 5 (2) |
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Basophils required for the induction of Th2 immunity to haptens and peptide antigens
Researchers from Kyoto University have reported that basophils play a central role in Th2 induction.
Medical research
May 07, 2013 |
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Exercise could reduce bone tumor growth
(Medical Xpress)—Weight-bearing exercise, often prescribed to combat bone loss, might have anti-cancer effects. Cornell biomedical researchers report that mechanical stimulation of cancerous bone, in making ...
Cancer
May 07, 2013 |
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Scientists find clues to some inherited heart diseases
(Medical Xpress)—Cornell researchers have uncovered the basic cell biology that helps explain heart defects found in diseases known as laminopathies, a group of some 15 genetic disorders that include forms ...
Medical research
May 07, 2013 |
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tPA: Clot buster and brain protector
(Medical Xpress)—Ever since its introduction in the 1990s, the "clot-busting" drug tPA has been considered a "double-edged sword" for people experiencing a stroke. It can help restore blood flow to the ...
Neuroscience
May 07, 2013 |
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FIU researchers develop new pathway to brain for medicine
Stumped for years by a natural filter in the body that allows few substances, including life-saving drugs, to enter the brain through the bloodstream, physicians who treat neurological diseases may soon have a new pathway ...
Medical research
May 06, 2013 |
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Major international study finds no link between viral infection and rapidly developing Type 1 diabetes in young children
Some of the earliest results from The Environmental Determinants of Diabetes in The Young (TEDDY) study - a major Europe-USA consortium exploring the causes of type 1 diabetes in children – has found no evidence for viral ...
Diabetes
May 06, 2013 |
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Researchers identify critical link in mammalian odor detection
Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally ...
Neuroscience
May 06, 2013 |
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