Normally the lining of the colon forms a series of steep hills and valleys. At the surface, where the hills peak, are functional colon cells that do the organ's work of absorption and secretion. Deep in the valleys are stem ...
Mar 29, 2023
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The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates ...
Nov 16, 2022
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Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...
Dec 13, 2021
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Using a novel integrative computational technique, scientists from Northwestern and the University of Illinois at Urbana-Champaign (UIUC) were able to classify disease conditions at the molecular level using epigenomic data ...
Mar 31, 2021
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A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University ...
Dec 2, 2020
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The transcriptional coregulator Swi-independent 3—or Sin3—switches on and off the genes that drive crucial biological processes during prenatal development, including cellular differentiation, maturation, survival, metabolism, ...
Sep 21, 2020
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Nanosecond pulsed electric fields (nsPEFs) produce strong electrical effects by focusing a high powered electrical pulse over a very short period of time. They are attracting attention as a method of physically stimulating ...
Aug 7, 2019
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Cells can change to a more specialized type in a process called cellular differentiation. Scientists have revealed that protein secretions by skin cells known as keratinocytes control the differentiation of subsurface skin ...
Jul 25, 2019
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One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo. In this important review ...
Jun 3, 2019
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The scientists of the UEx Molecular Biology of Cancer Research Group seek to uncover the physiological mechanisms of cancer stem cells, which are responsible for the progression of the tumour. Thus, they are working on identifying ...
Mar 6, 2018
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