Diseases, Conditions, Syndromes

How does SARS-CoV-2 evade our immune defenses?

How does SARS-CoV-2 evade our immune defenses? It's a good question, actually. When SARS-CoV-2 defeats host defenses, we need to know how it does so, and conversely, when host defenses prevail, that also needs to be understood. ...

Medical research

Medical researchers decoding the aging process

Scientists are beginning to decode the complex biology of aging and are optimistic that recent advances in research may lead to treatments that can slow or even reverse degeneration and disease.

Genetics

Scientists decipher the 3-D structure of the human genome

Scientists have deciphered the three-dimensional structure of the human genome, paving the way for new insights into genomic function and expanding our understanding of how cellular DNA folds at scales that dwarf the double ...

Immunology

Faulty DNA disposal system found to cause inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy. ...

Medical research

How mitochondrial DNA defects cause inherited deafness

(Medical Xpress) -- Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed cell death. ...

HIV & AIDS

HIV can develop resistance to CRISPR/Cas9

The CRISPR/Cas9 gene-editing platform may need a little bit more tweaking before it can be used as an effective antiviral, reports a study published April 7 in Cell Reports. Researchers who used CRISPR/Cas9 to mutate HIV-1 ...

Diseases, Conditions, Syndromes

High iron, copper levels block brain-cell DNA repair

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions. One is ...

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