Senescent cells—those that have lost the ability to divide—accumulate with age and are key drivers of age-related diseases, such as cancer, dementia and cardiovascular disease. In a new study, a team led by University ...
Jun 30, 2022
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A Florida State University College of Medicine researcher has made a discovery that alters our understanding of how the body's DNA repair process works and may lead to new chemotherapy treatments for cancer and other disorders.
Mar 8, 2022
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Although visible signs of aging are usually unmistakable, unraveling what triggers them has been quite a challenge. Researchers at Baylor College of Medicine and collaborating institutions have discovered that a cellular ...
Aug 2, 2021
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Researchers at Princeton have determined how five cellular proteins contribute to an essential step in the life cycle of hepatitis B virus (HBV). The article describing these findings appeared March 11, 2021 in the journal ...
Mar 11, 2021
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Proteins are crucial to all cellular processes. So for a cell to stay viable, it has to keep its proteins in shape. In technical terms, it's called protein folding, and it refers to the process by which proteins assume their ...
Feb 1, 2021
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A new 'toolkit' to repair damaged DNA that can lead to ageing, cancer and Motor Neurone Disease (MND) has been discovered by scientists at the Universities of Sheffield and Oxford.
Mar 9, 2020
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Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence. This pathway may be modulated during senescence-inducing chemotherapy ...
Feb 19, 2020
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Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men's genomes—the complete set of genetic material ...
Oct 8, 2019
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Scientists have revealed how the typhoid toxin works to hijack DNA repair machines and accelerate the aging of cells, a breakthrough that could pave the way for new strategies to combat the killer disease.
Sep 6, 2019
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The CRISPR/Cas9 gene-editing platform may need a little bit more tweaking before it can be used as an effective antiviral, reports a study published April 7 in Cell Reports. Researchers who used CRISPR/Cas9 to mutate HIV-1 ...
Apr 7, 2016
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