A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structures. Specifically, changes occur in the protective processes of apoptosis and cellular senescence, ...
Jul 13, 2016
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The neurodegeneration that occurs in Parkinson's disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies. It ...
Jun 23, 2016
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University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that ...
Mar 17, 2016
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University of California, Irvine researchers with the School of Medicine have identified the mechanism by which valproic acid controls epileptic seizures, and by doing so, also revealed an underlying factor of seizures.
Sep 14, 2015
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Researchers reveal how cells in the peripheral nervous system (PNS) degrade myelin after nerve injury, a process that fails to occur in the central nervous system (CNS). The study appears in The Journal of Cell Biology.
Jul 6, 2015
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Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully ...
Jun 8, 2015
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Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for ...
May 22, 2015
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Researchers in Singapore are gaining further insight into how the mechanical environment of cells drives fundamental cellular processes such as motility, growth and survival. These processes are integral to many clinical ...
Mar 19, 2015
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Researchers have developed a novel three-dimensional, multiscale and multicomponent model of endothelial cells monolayer, the inner lining of artery, to identify the cellular mechanisms involved in cardiovascular diseases ...
Feb 25, 2015
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Throughout our lives, our brains adapt to what we learn and memorise. The brain is indeed made up of complex networks of neurons and synapses that are constantly re-configured. However, in order for learning to leave a trace, ...
Jul 17, 2014
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