News tagged with cellular model
Metabolic biomarkers can predict mortality in the ICU
A metabolic profile of intensive care unit (ICU) patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.
Diseases, Conditions, Syndromes
May 20, 2013 |
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Large animal models of Huntington's disease offer new and promising research options
Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology. Large animal models, such as domesticated ...
Neuroscience
Apr 22, 2013 |
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Study shines light on how stress circuits learn
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including ...
Neuroscience
Apr 07, 2013 |
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Improving the search for new schizophrenia treatments
(Medical Xpress)—Controlling the symptoms of schizophrenia is the job of antipsychotic drugs which block a set of specific neural signals. But the way these drugs work can lead to a host of severe and debilitating ...
Psychology & Psychiatry
Apr 05, 2013 |
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Promoting muscle regeneration in a mouse model of muscular dystrophy
Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in the protein dystrophin. Dystrophin functions to protect muscle cells from injury and loss of functional dystrophin results ...
Medical research
Apr 01, 2013 |
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Team discovers how cells distinguish friend from foe
(Medical Xpress)—Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by ...
Immunology
Apr 01, 2013 |
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Age-related dementia may begin with neurons' inability to dispose of unwanted proteins
A team of European scientists from the University Medical Center Hamburg-Eppendorf (UKE) and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne in ...
Alzheimer's disease & dementia
Mar 05, 2013 |
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Fragile X makes brain cells talk too much, research shows
The most common inherited form of mental retardation and autism, fragile X syndrome, turns some brain cells into chatterboxes, scientists at Washington University School of Medicine in St. Louis report.
Neuroscience
Feb 20, 2013 |
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Bioelectric signals can be used to detect early cancer
Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...
Medical research
Feb 01, 2013 |
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Scientists use luminescent mice to track cancer and aging in real-time
In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth ...
Medical research
Jan 17, 2013 |
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Promising new finding for therapies to treat persistent seizures in epileptic patients
In a promising finding for epileptic patients suffering from persistent seizures known as status epilepticus, researchers reported today that new medication could help halt these devastating seizures. To ...
Neuroscience
Jan 16, 2013 |
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Development of new cornea endothelial cell lines provides powerful tool for understanding corneal cell biology
Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. Cell loss due to aging or corneal endothelial disorders, such ...
Ophthalmology
Dec 27, 2012 |
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Hard-to-treat Myc-driven cancers may be susceptible to drug already used in clinic
Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers ...
Cancer
Dec 14, 2012 |
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Enzyme inhibition protects against Huntington's disease damage in two animal models
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal ...
Neuroscience
Nov 29, 2012 |
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Study shows how chronic inflammation can cause cancer
A hormone-like substance produced by the body to promote inflammation can cause an aggressive form of leukemia when present at high levels, according to a new study by researchers at the Ohio State University Comprehensive ...
Cancer
Nov 12, 2012 |
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