News tagged with cellular pathways


Hundreds of alterations and potential drug targets to starve cancer tumors identified

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...

Cancer created Apr 21, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists use nature against nature to develop an antibiotic with reduced resistance

A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacter ...

Medications created Apr 10, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study shines light on how stress circuits learn

Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including ...

Neuroscience created Apr 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice

(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...

Cancer created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers identify brain pathway triggering impulsive eating

New research from the University of Georgia has identified the neural pathways in an insect brain tied to eating for pleasure, a discovery that sheds light on mirror impulsive eating pathways in the human ...

Medical research created Feb 28, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome

A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation

Cancer created Feb 12, 2013 | popularity not rated yet | comments 0

New insight into RASopathy-associated lymphatic defects

The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.

Diseases, Conditions, Syndromes created Feb 08, 2013 | popularity not rated yet | comments 0

Trapping malaria parasites inside host cell basis for new drugs

One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self. Researchers from ...

Medical research created Jan 16, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Sensory hair cells regenerated, hearing restored in mammal ear

Hearing loss is a significant public health problem affecting close to 50 million people in the United States alone. Sensorineural hearing loss is the most common form and is caused by the loss of sensory ...

Neuroscience created Jan 09, 2013 | popularity 4.7 / 5 (39) | comments 16 | with audio podcast

Small peptide ameliorates autoimmune skin blistering disease in mice

Pemphigus vulgaris is a life-threatening autoimmune skin disease that is occurs when the body's immune system generates antibodies that target proteins in the skin known as desomogleins. Desmogleins help to form the adhesive ...

Immunology created Jan 09, 2013 | popularity 5 / 5 (1) | comments 0

Scientists find mechanism that triggers immune responses to DNA

(Medical Xpress)—Free-floating pieces of DNA in a cell's watery interior can mean bad things: invading viruses, bacteria, or parasites, ruptured cellular membranes, or disease. Genetic material is meant to be contained ...

Medical research created Dec 21, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Ability to chart the molecular progress of diabetes brings personalized medicine closer to realization

Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments ...

Diabetes created Dec 19, 2012 | popularity 5 / 5 (1) | comments 0

Research may have important implications for combating diabetes

(Medical Xpress)—Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes.

Diabetes created Dec 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel drug therapy targets aggressive form of non-Hodgkin's lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL ...

Cancer created Dec 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Targeting downstream proteins in cancer-causing pathway shows promise in cell, animal model

The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell's powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all "hard-to-treat" cancers have a ...

Cancer created Nov 13, 2012 | popularity 5 / 5 (1) | comments 0