News tagged with cellular pathways
Sensory hair cells regenerated, hearing restored in mammal ear
Hearing loss is a significant public health problem affecting close to 50 million people in the United States alone. Sensorineural hearing loss is the most common form and is caused by the loss of sensory ...
Neuroscience
Jan 09, 2013 |
4.7 / 5 (39) |
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Discovery shows medications can treat inflammation without increasing risk for infection
In a discovery that can fundamentally change how drugs for arthritis, and potentially many other diseases, are made, University of Utah medical researchers have identified a way to treat inflammation while potentially minimizing ...
Inflammatory disorders
Nov 11, 2012 |
4.8 / 5 (9) |
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Researchers discover key to immune cell's 'internal guidance' system
University of British Columbia researchers have discovered the molecular pathway that enables receptors inside immune cells to find, and flag, fragments of pathogens trying to invade a host.
Immunology
Feb 05, 2012 |
5 / 5 (6) |
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
5 / 5 (4) |
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Scientists discover mechanism that controls obesity, atherosclerosis and potentially cancer
Scientists from the Institute of Molecular and Cell Biology (IMCB) have discovered a new signalling pathway that controls both obesity and atherosclerosis. The team demonstrated, for the first time, that mice deficient in ...
Medical research
Jul 03, 2012 |
5 / 5 (3) |
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Scientists find mechanism that triggers immune responses to DNA
(Medical Xpress)—Free-floating pieces of DNA in a cell's watery interior can mean bad things: invading viruses, bacteria, or parasites, ruptured cellular membranes, or disease. Genetic material is meant to be contained ...
Medical research
Dec 21, 2012 |
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Scientists use nature against nature to develop an antibiotic with reduced resistance
A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacter ...
Medications
Apr 10, 2013 |
5 / 5 (3) |
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Researchers identify key genes and prototype predictive test for schizophrenia
An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate ...
Genetics
May 15, 2012 |
4.7 / 5 (3) |
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New approach to link genome-wide association signals to biological function
Researchers have developed a new strategy to improve the outcome of genome-wide association (GWA) studies.
Genetics
Jun 30, 2011 |
5 / 5 (2) |
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Researchers use genomics to identify a molecular-based treatment for a viral skin cancer
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...
Cancer
May 09, 2012 |
5 / 5 (2) |
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Using rabies virus, researcher tracks inputs to dopamine neurons
A genetically-modified version of the rabies virus is helping scientists at Harvard to trace neural pathways in the brain, a research effort that could one day lead to treatments for Parkinson's disease and addiction.
Neuroscience
Jun 06, 2012 |
5 / 5 (2) |
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Using planarian flatworms to understand organ regeneration
Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.
Medical research
Oct 25, 2012 |
5 / 5 (2) |
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Growth hormone helps repair the zebrafish ear
Loud noise, especially repeated loud noise, is known to cause irreversible damage to the hair cells inside the cochlea and eventually lead to deafness. In mammals this is irreversible, however both birds and fish are able ...
Neuroscience
Sep 02, 2011 |
5 / 5 (1) |
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How mitochondrial DNA defects cause inherited deafness
(Medical Xpress) -- Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed ...
Medical research
Feb 17, 2012 |
5 / 5 (1) |
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Cortex development depends on a protein
As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.
Medical research
Oct 02, 2012 |
5 / 5 (1) |
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