New research uncovers diverse metabolic roles for PML tumor suppressor gene
Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, ...
Cancer
Aug 30, 2012 |
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Fitting Kv potassium channels in the PIP2 puzzle
A recent study in the Journal of General Physiology brings new insights to an area of ion channel regulation: whether voltage-gated potassium (Kv) channels can be regulated by physiological changes to PIP ...
Medical research
Aug 27, 2012 |
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Gene 'switch' may explain DiGeorge syndrome severity
The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.
Genetics
Aug 23, 2012 |
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The scientific side of steroid use and abuse
Leslie Henderson investigates the cellular basis for behavioral changes seen with the abuse of anabolic androgenic steroids. In her laboratory work, Henderson has looked at three major behavioral systems typically ...
Addiction
Aug 06, 2012 |
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Protein involved in DNA replication, centrosome regulation linked to dwarfism, small brain size
Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise ...
Genetics
Jul 31, 2012 |
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Cell research opens new avenues in combating neurodegenerative diseases
Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular ...
Neuroscience
Jul 20, 2012 |
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Arsenic for better drugs and cleaner crops
Research carried out at the University of Gothenburg may lead to more effective arsenic-containing drugs. The results may also lead to more resistant plants, and crops with a limited absorption and storage of arsenic.
Medications
Jun 25, 2012 |
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Aging and breast cancer: Researchers uncover cellular basis for age-related breast cancer vulnerability
It is well-known that the risks of breast cancer increase dramatically for women over the age of 50, but what takes place at the cellular level to cause this increase has been a mystery. Some answers and the ...
Cancer
Jun 04, 2012 |
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Elimination of two ribosome subunits activates cell cycle control
Alterations in the formation of ribosomes (the elements of the cell where proteins are made) cause the induction of p53 protein and cell cycle disruption. This process is crucial to understand fundamental biological processes ...
Genetics
May 22, 2012 |
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Could the ways animals regenerate hair and feathers lead to clues to restore human fingers and toes?
This summer's action film, "The Amazing Spider-Man," is another match-up between the superhero and his nemesis the Lizard. Moviegoers and comic book fans alike will recall that the villain, AKA Dr. Curt Connors, was a surgeon ...
Medical research
May 10, 2012 |
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Study finds cancer-fighting goodness in cholesterol
A Simon Fraser University researcher is among four scientists who argue that cholesterol may slow or stop cancer cell growth. They describe how cholesterol-binding proteins called ORPs may control cell growth in A Detour ...
Cancer
Apr 19, 2012 |
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Problems in recycling cellular waste linked to clogged arteries
(Medical Xpress) -- Researchers at Washington University School of Medicine in St. Louis have found that problems with a digestive process in cells can clog arteries.
Cardiology
Apr 05, 2012 |
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Newly found protein helps cells build tissues
As they work together to form body parts, cells in developing organisms communicate like workers at a construction site. The discovery of a new signaling molecule in flies by Brown University biologists not only helps explain ...
Medical research
Apr 02, 2012 |
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Protein Aurora-A is found to be associated with survival in head and neck cancer
Researchers at Fox Chase Cancer Center in Philadelphia have found that a protein associated with other cancers appears to also be important in head and neck cancer, and may consequently serve as a good target for new treatments. ...
Cancer
Apr 01, 2012 |
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Researchers find important 'target' playing role in tobacco-related lung cancers
Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce ...
Cancer
Feb 09, 2012 |
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