Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, aging, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA replication ...
Jan 10, 2024
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In people with Alzheimer's disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain.
Nov 27, 2023
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A new research paper titled "Gene expression signatures of human senescent corneal and conjunctival epithelial cells" has been published in Aging.
Oct 2, 2023
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Cells are capable of translating mechanical changes into biological responses. This process is known as mechanotransduction and plays a fundamental role in the progression of solid tumors, such as breast cancer.
Sep 14, 2023
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More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited. It is a major national healthcare and public ...
May 26, 2023
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As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...
Nov 14, 2022
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Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer. According to the newly published study, R-spondin, which enhances the growth of healthy cells in the gut, ...
Sep 23, 2020
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With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism. Their discovery, which appears ...
Nov 21, 2019
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After a flesh wound, skin cells march forward to close the gap and repair the injury. Findings from a team led by Leah Vardy at A*STAR's Skin Research Institute of Singapore now demonstrate how a carefully regulated set of ...
Jan 15, 2019
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An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and ...
Mar 8, 2017
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