Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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Age-related dementia may begin with neurons' inability to dispose of unwanted proteins
A team of European scientists from the University Medical Center Hamburg-Eppendorf (UKE) and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) at the University of Cologne in ...
Alzheimer's disease & dementia
Mar 05, 2013 |
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Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice
(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...
Cancer
Mar 05, 2013 |
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Discovery opens door to new drug options for serious diseases
Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.
Medical research
Mar 04, 2013 |
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Researchers find that two antagonistic proteins help keep leukemia at bay, pointing to new potential treatments
Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published ...
Cancer
Feb 27, 2013 |
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Cervical cancer: First 3-D image of an HPV oncoprotein
(Medical Xpress)—For the first time, researchers from the Laboratoire biotechnologie et signalisation cellulaire at the Strasbourg-based Ecole supérieure de biotechnologie (CNRS/Université de Strasbourg) and Institut ...
Cancer
Feb 15, 2013 |
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How chromosomes keep their loose ends loose
We take it for granted that our chromosomes won't stick together, yet this kind of cellular disaster would happen constantly were it not for a protein called TRF2. Now, scientists at The Scripps Research Institute (TSRI) ...
Medical research
Feb 06, 2013 |
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Scientists find key element of lupus, suggesting better drug targets
A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The ...
Medical research
Feb 04, 2013 |
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Providing brain cells with the 3rd dimension to grow outside the body
Researchers at Sahlgrenska Academy in collaboration with Chalmers University of Technology developed a unique Bioactive3D culture system for brain cells. This system gives new possibilities to study cell-cell ...
Medical research
Jan 25, 2013 |
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Scientists find cancer-causing virus in the brain, potential connection to epilepsy
Researchers at Shriner's Hospital Pediatric Research Center at the Temple University School of Medicine, and the University of Pennsylvania have evidence linking the human papillomavirus 16 (HPV16) – the most common cause ...
Neuroscience
Jan 24, 2013 |
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Circadian rhythms can be modified for potential treatment of disorders
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Cardiology
Jan 22, 2013 |
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Immune system foiled by a hairpin
The innate immune system detects invasive pathogens and activates defense mechanisms to eliminate them. Pathogens, however, employ a variety of tricks to block this process. A new study shows how the measles virus thwarts ...
Immunology
Jan 22, 2013 |
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The new age of proteomics: An integrative vision of the cellular world
The enormous complexity of biological processes requires the use of highperformance technologies —also known as 'omics'—, that are capable of carrying out complete integrated analyses of the thousands of molecules ...
Genetics
Jan 17, 2013 |
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Trapping malaria parasites inside host cell basis for new drugs
One of the most insidious ways that parasitic diseases such as malaria and toxoplasmosis wreak their havoc is by hijacking their host's natural cellular processes, turning self against self. Researchers from ...
Medical research
Jan 16, 2013 |
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Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...
Cancer
Jan 16, 2013 |
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