Scientists discover marker to identify, attack breast cancer stem cells
Breast cancer stem cells wear a cell surface protein that is part nametag and part bull's eye, identifying them as potent tumor-generating cells and flagging their vulnerability to a drug, researchers at The University of ...
Cancer
May 16, 2012 |
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Researchers use genomics to identify a molecular-based treatment for a viral skin cancer
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...
Cancer
May 09, 2012 |
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Clusters of cooperating tumor-suppressor genes are found in large regions deleted in common cancers
Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer ...
Cancer
May 07, 2012 |
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Gatekeeper of brain steroid signals boosts emotional resilience to stress
A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress ...
Neuroscience
Apr 23, 2012 |
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Study finds cancer-fighting goodness in cholesterol
A Simon Fraser University researcher is among four scientists who argue that cholesterol may slow or stop cancer cell growth. They describe how cholesterol-binding proteins called ORPs may control cell growth in A Detour ...
Cancer
Apr 19, 2012 |
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Researchers find potential for new uses of old drug
(Phys.org) -- Researchers in Canada, Scotland and Australia have discovered that salicylate, the active ingredient in aspirin, directly increases the activity of the protein AMPK (AMP-activated protein kinase), a key player ...
Medications
Apr 19, 2012 |
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Metal binding important for metformin action
(HealthDay) -- The ability of metformin to bind mitochondrial copper may be essential to its mechanism of action, according to a study published online April 9 in Diabetes.
Diabetes
Apr 14, 2012 |
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Researchers identify key regulator of inflammatory response
(Medical Xpress) -- Researchers at Boston University School of Medicine (BUSM) have identified a gene that plays a key role in regulating inflammatory response and homeostasis. These findings could help lead to the development ...
Inflammatory disorders
Apr 12, 2012 |
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Study reveals insight into how key protein protects against viral infections
Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for ...
Immunology
Apr 02, 2012 |
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Protein Aurora-A is found to be associated with survival in head and neck cancer
Researchers at Fox Chase Cancer Center in Philadelphia have found that a protein associated with other cancers appears to also be important in head and neck cancer, and may consequently serve as a good target for new treatments. ...
Cancer
Apr 01, 2012 |
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Map of substrate-kinase interactions may lead to more effective cancer drugs
(Medical Xpress) -- Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close ...
Cancer
Mar 27, 2012 |
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Collaboration rapidly connects fly gene discovery to human disease
A collaborative study by scientists at Baylor College of Medicine (BCM) and the Montreal Neurological Institute of McGill University, and published March 20 in the online, open access journal PLoS Biology, has discovered that m ...
Genetics
Mar 20, 2012 |
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Cuba to test new AIDS vaccine on humans
Cuba's top biotech teams have successfully tested a new AIDS vaccine on mice, and are ready to soon begin human testing, a leading researcher told a biotechnology conference in Havana on Monday.
HIV & AIDS
Mar 06, 2012 |
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Scientists create molecular map to guide treatment of multiple sclerosis
A team of scientists from the Scripps Research Institute, collaborating with members of the drug discovery company Receptos, has created the first high-resolution virtual image of cellular structures called ...
Medical research
Feb 16, 2012 |
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Researchers pave the way for improving treatment for Type 2 diabetes
In a study published last week in the prestigious Proceedings of the National Academy of Sciences of the United States of America, a team led by Dr. Vincent Poitout of the University of Montreal Hospital Research Centre (CRCHU ...
Diabetes
Feb 07, 2012 |
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