Gene linked to pancreatic cancer growth, study finds
A mutant protein found in nearly all pancreatic cancers plays a role not only in the cancer's development but in its continued growth, according to a new study from University of Michigan Comprehensive Cancer ...
Cancer
Jan 31, 2012 |
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Researchers indentify a cell-permeable peptide that inhibits hepatitis C
Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks viral replication, which can lead to liver cancer and cirrhosis.
Diseases, Conditions, Syndromes
Jan 31, 2012 |
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Three is the magic number: A chain reaction required to prevent tumor formation
Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Cancer
Jan 20, 2012 |
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Scientists uncover novel mechanism of glioblastoma development
Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally ...
Cancer
Jan 18, 2012 |
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ISG15: A novel therapeutic target to slow breast cancer cell motility
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and ...
Cancer
Jan 11, 2012 |
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New components of antiviral pathway discovered
Scientists studying how mammals detect microbes have discovered new components in a crucial pathway that allows immune cells to detect viral invaders. Their research not only deepens the understanding of antiviral responses, ...
Medical research
Dec 22, 2011 |
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Breakthrough in regulating fat metabolism
Scientists at Warwick Medical School have made an important discovery about the mechanism controlling the body's 'fat switch', shedding new light on our understanding of how proteins regulate appetite control and insulin ...
Medical research
Dec 08, 2011 |
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Drug reverses aging-associated changes in brain cells
Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study in the December 7 issue of The Journal of Ne ...
Neuroscience
Dec 07, 2011 |
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Cell molecule identified as central player in the formation of new blood vessels
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein ...
Medical research
Nov 28, 2011 |
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Internal skin cancer prevention: Repairing UV damage in the skin
(Medical Xpress) -- Scientists at the Friedrich Miescher Institute for Biomedical Research (FMI) of the Novartis Research Foundation have elucidated the mechanisms underlying the repair of UV-induced damage ...
Cancer
Nov 24, 2011 |
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Recipient's immune system governs stem cell regeneration
A new study in Nature Medicine describes how different types of immune system T-cells alternately discourage and encourage stem cells to regrow bone and tissue, bringing into sharp focus the importance of the transplant recipient's ...
Medical research
Nov 20, 2011 |
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New study uncovers how brain cells degrade dangerous protein aggregates
Researchers at the RIKEN Brain Science Institute (BSI) have discovered a key mechanism responsible for selectively degrading aggregates of ubiquitinated proteins from the cell. Their findings indicate that ...
Medical research
Nov 07, 2011 |
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Gene regulatory protein is reduced in bipolar disorder
Low levels of a brain protein that regulates gene expression may play a role in the origin of bipolar disorder, a complex and sometimes disabling psychiatric disease. As reported in the latest issue of Bipolar Disorders, the jo ...
Psychology & Psychiatry
Oct 25, 2011 |
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Findings suggest how cancer cells can become resistant to DNA damage-inducing treatments
An international team of scientists led by UC Davis researchers has discovered that DNA repair in cancer cells is not a one-way street as previously believed. Their findings show instead that recombination, an important DNA ...
Cancer
Oct 23, 2011 |
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Protein family key to aging, cancer
The list of aging-associated proteins known to be involved in cancer is growing longer, according to research by investigators at Vanderbilt-Ingram Cancer Center and the National Institutes of Health (NIH).
Cancer
Oct 17, 2011 |
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