Neuroscience
Detailed structure illuminates brain-enhancing drug's action
A detailed picture of a brain-boosting experimental drug could one day help researchers tailor it for use in human clinical trials.
Mar 29, 2018
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News tagged with cellular proteins
Neuroscience
Research reveals atomic-level changes in ALS-linked protein
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases ...
Jan 18, 2018
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65
Neuroscience
Neuroscientists build case for new theory of memory formation
Learning and memory are generally thought to be composed of three major steps: encoding events into the brain network, storing the encoded information, and later retrieving it for recall.
Oct 23, 2017
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Neuroscience
Cellular quality control process could be Huntington's disease drug target
The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative ...
Feb 13, 2017
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65
Medical research
Not all organs age alike
Aging is typically thought of as the gradual decline of the whole body, but new research shows that age affects organs in strikingly different ways. A study published September 17 in Cell Systems provides the first comprehensive ...
Sep 17, 2015
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225
Neuroscience
Scientists identify new drug target to treat ALS
Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully ...
Jun 8, 2015
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Medical research
Researchers identify a new trigger of cellular self-destruction
Researchers have identified a bacterial protein that triggers a self-inflicted cell death pathway in immune system cells and could lead to a better understanding of an important cellular structure.
Mar 17, 2015
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67
Medical research
Clipping proteins that package genes may limit abnormal cell growth in tumors
Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published ...
Nov 21, 2014
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Oncology & Cancer
Rare developmental disorder linked to tumor-suppressing protein
CHARGE, which affects 1 in 10,000 babies, is an acronym whose letters stand for some of the more common symptoms of the condition: coloboma of the eye, heart defects, atresia of the choanae, retardation of growth and/or development, ...
Aug 3, 2014
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Medical research
Architecture of signaling proteins enhances knowledge of key receptors
A team of scientists from Duke Medicine, the University of Michigan and Stanford University has determined the underlying architecture of a cellular signaling complex involved in the body's response to stimuli such as light ...
Jun 22, 2014
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